西北农林科大动物科技学院导师介绍:张智英
一、个人简历 张智英,男,1958年2月生,陕西兴平人,汉族。加拿大生物学博士(后),西北农林科技大学教授、博
五、主要学术论文
1. Zhiying Zhang, Melissa Z. Mui, Francine Chan, Diana E. Roopchand, Richard C. Marcellus, Paola Blanchette, Suiyang Li, Albert M. Berghuis and Philip E. Branton. Genetic analysis of B55α/Cdc55 PP2A subunits: Association with the adenovirus E4orf4 protein. Journal of Virology,2010, (submitted)
2. Li S, Brignole C, Marcellus R, Thirlwell S, Binda O, McQuoid MJ, Ashby D, Chan H, Zhang Z, Miron MJ, Pallas DC, Branton PE. The Adenovirus E4orf4 Protein Induces G2/M Arrest and Cell Death by Blocking PP2A Activity Regulated by the B55 Subunit. Journal of Virology,2009, Jun, 17(SCI 收录:IF=6.033).
3. 王令 张存芳张智英 锌指核酸酶在基因组靶向修饰中的应用 中国生物化学与分子生物学报 2009
4. Han ZS, Li QW, Zhang Z, Yu YS, Xiao B, Wu SY, Jiang ZL, Zhao HW, Zhao R, Li J. Adenoviral Vector Mediates High Expression Levels of Human Lactoferrin in the Milk of Rabbits. J. Microbiol Biotechnol. 2008. Jan; 18(1): 153-159. (SCI 收录:IF=2.058)
5. Han ZS, Li QW, Zhang Z, Xiao B, Gao DW, Wu SY, Li J, Zhao HW, Jiang ZL, Hu JH. High-level expression of human lactoferrin in the milk of goats by using replication-defective adenoviral vectors. Protein. Expr. Purif. 2007. May;53(1):225-31. (SCI 收录:IF=1.867)
6. Marshall KS, Zhang Z, Curran J, Derbyshire S, Mymryk JS. An improved genetic system for detection and analysis of protein nuclear import signals. BMC Molecular Biology. 2007. Jan 25; 8:6. (SCI 收录:IF=3.50)
7. Avvakumov N, Sahbegovic M, Zhang Z, Shuen M, Mymryk JS. Analysis of DNA binding by the adenovirus 5 E1A oncoprotein. Journal of General Virology. 2002 Mar; 83(Pt 3):517-24. (SCI 收录:IF=3.410)
8. Han ZS, Li QW, Zhang ZY, Yu YS, Xiao B, Wu SY, Jiang ZL, Zhao HW, Zhao R, Li J. Adenoviral vector mediates high expression levels of human lactoferrin in the milk of rabbits. J Microbiol Biotechnol. 2008 Jan;18(1):153-9.
9. Zhang, Z. Smith M. and Mymryk JS. Interaction of the E1A oncoprotein with Yak1p, a novel regulator of yeast pseudohyphal differentiation, and related mammalian kinases. Mol.Biol. Cell. 2001,12(3): 699-710. (SCI 收录:IF=9.376)
10. Zhang, Z. and Martineau D. Walleye dermal sarcoma virus: orfA N-terminal End inhibits the activity of a reporter gene directed by eukaryotic promoters and has a negative effect on the growth of fish and mammalian cells. Journal of Virology, 1999,73 (10), 8884-8889. (SCI 收录:IF=6.033)
11. Zhang, Z., and Martineau D. Phylogenetic analysis of walleye dermal sarcoma virus by comparison of gag, pol and env partial sequences, Virology, 1996, 225:406-412. (SCI 收录:IF=3.901)
12. Zhang, Z. Kim E. and Martineau D. Functional characterization of a piscine retrovirus promoter. Journal of General Virology. 1999, 80(12), 3065-3072. (SCI 收录:IF=3.410)
13. Zhang, Z., and Martineau D. Single-tube heminested PCR coupled with touchdown PCR for the analysis of the walleye dermal sarcoma virus env gene, Journal of Virological Methods 1996,60:29-37. (SCI 收录:IF=1.464)
六、会议摘要
1.Zhang, Z. Smith M and Mymryk J. Adenovirus E1A modulates yeast pseudohyphal growth. (Abstract) presented in Yeast Genomic and Human Diseases in Vancouver, Canada. 1999.
2.Zhang, Z. Smith M and Mymryk J. Adenovirus E1A modulates yeast pseudohyphal growth. (Abstract) presented in 60th Anniversary of th Department of Microbiology and Immunology, University of Western Ontario. 1999.
3.Zhang, Z. and Martineau D. Regulation of walleye dermal sarcoma virus transcription. (abstract) Cold Spring Harbor Laboratory, Retroviruses, 1996, May.
4.Zhang, Z. and Martineau D. A new fish retrovirus (WDSV) associated with skin tumor. 4th colloque de biotechnologie de l'Universite de Montreal (presentation), 1995.
七、应邀大会发言
1. 2010年6月14号陕西省生物化学与分子生物学年会,大会特邀反应:Designing Zinc-Finger Nucleases for Genome Editing
2. 2009年10月10日,第十五次全国动物遗传育种学术讨论会,大会特邀发言:Designing Zinc-Finger Nucleases for Animal Genome Editing (人工锌指核酸酶技术与动物基因组定点整合)。
3. 2009年7月2号:华夏农耕文化渊源体验营,特邀发言:Introduction to Biotechnology (生物技术与现代生活的渊源)。
4. 2008年7月20日, 陕西省生物化学和分子生物学年会,大会特邀发言:Mechanism of Adenovirus E4orf4 Killing Cancer Cells。
5. 2008年11月6日,第15届中国杨凌农业高新技术论坛,大会发言:Designing Zinc Finger Nucleases for Animal Gene Targeting Modification。
6. 2008 - 2009年间,在动物科技学院第一会议室与美国马里兰大学、加拿大麦吉尔大学、圭尔夫大学等多位教授进行多次相关的学术讨论与交流。
7.2008 - 2009年间,在动物科技学院第一会议室为本院青年教师和研究生讲授病毒载体、酵母杂交系统等相关知识的学术报告。
八、联系方式
Email: zzhang888@gmail.com
zhangzhy@nwsuaf.edu.cn
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