华南理工大学生物科学与工程学院导师介绍:方颖
姓名:方颖 性别:女 职称:副教授 学院:生物科学与工程学院 研究方向:血栓及肿瘤转移过程中的细
国际合作交流
本实验室,注重国际学术交流与合作交流,学术气氛活跃。与美国乔治亚理工学院、圣路易斯华盛顿大学、贝勒医学院和宾州州立大学、哥伦比亚大学及加拿大渥太华大学等建立了密切学术联系。每年选派3-5名研究生参加国际和国内学术交流活动,近三年,并有三人次获大会青年科学家或优秀研究生论文奖。
近期发表主要论文
1. Xiang Fang, Ying Fang*, Li Liu, Guangjian Liu, Jianhua Wu. 2012. Mapping Paratope on Antithrombotic Antibody 6B4 to Epitope Platelet Glycoprotein Ibalpha via Molecular Dynamic Simulations. PLoS ONE 7(7): e42263.
2. Quhuan Li, Ying Fang, Xiaoru Ding, Jianhua Wu. 2012. Force-dependent bond dissociation govern rolling of HL-60 cells through E-selectin. Experimental Cell Research. 318(14): 1649-1658
3. 严翠婷,黄庆生,章芬,方颖*,2012, 基于图像配准分析物种进化关系的新方法,基因组学与应用生物学,31(3): 212-221
4. Liu, L., Y. Fang, Q. Huang and J. Wu. 2011. A rigidity-enhanced antimicrobial activity: a case for linear cationic α-helical peptide HP(2–20) and its four analogues. PLoS ONE 6(1): e16441.
5. Sun, T., Q. Huang, Y. Fang and J. Wu. 2011. FurinDB: A database of 20-Residues furin cleavage site matiffs, substrates and their associated druges. Int. J. Mol. Sci. 12(2): 1060-1065.
6. X. Fang, Y. Fang and J. Wu. 2011. Computational modeling of the Antithrombotic Antibody SZ2 in complex with GPIbα. Proc. of 5th International Conference on Bioinformatics and Biomedical Engineering (iCBBE), May 10-12, 2011. Wuhan, China. (10.1109/icbbe.2011.5780046)
7. G. Liu, Y. Fang and J. Wu. 2011. Type 2B Mutations Destabilize VWF A1 Domain: A Molecular Dynamics Simulation Study. Proc. of 5th International Conference on Bioinformatics and Biomedical Engineering (iCBBE), May 10-12, 2011. Wuhan, China. (10.1109/icbbe.2011.5780047)
8. Y.Xiang, Y.Fu, J. Wu, Y.Fang and S.Feng. 2011. Analysis of high-frequency risk factors among patients with Coronary Heart Disease in Guangzhou. Proc. of 5th International Conference on Bioinformatics and Biomedical Engineering (iCBBE), May 10-12, 2011. Wuhan, China. (10.1109/icbbe.2011.5781613)
9. 项钰,吴建华,方颖,冯常森,2011. 广州地区心血管病患者危险因子与血脂水平的分析. 广东医学.32(9):1185-1188
10. 黄强, 凌颖琛, 李趣欢, 吴建华, 方颖. 2010.通过流动腔实验测量HL-60细胞微绒毛弹性.医用生物力学.25(4):19-24.
11. Fang, Y,, J. Wu, R.P. McEver and C. Zhu. 2009. Bending rigidities of cell surface molecules P-selectin and PSGL-1, J. of Biomechanics, 42: 303-307.
12. L. Liu, Q. Huang, Y. Fang, J. Wu. 2009. Flexibility, a possible dominant factor on the activity of antimicrobial peptides. Proc. of the 4th WACBE World Congress on Bioengineering 2009. p308. (第九届世界华人生物医学工程大会)荣获WACBE Young Investigator Award。WACBE青年科学家奖.
13. Tolentino, T.P, J. Wu, V.I. Zarnitsyna, Y. Fang, M.L. Dustin and C. Zhu. 2008. Measuring diffusion and binding kinetics by contact area FRAP. Biophysical Journal. 95(2): 920-930
14. Wu, J, Y. Fang, V.I. Zarnitsyna, T.P. Tolentino, M.L. Dustin and C. Zhu. 2008. A coupled diffusion- kinetics model for analysis of contact area FRAP experiment. Biophysical Journal. 95(2): 910- 919.
15. 方颖, 吴建华. 2008. 受弹性生物试件约束的矩形AFM悬臂梁的热响应. 生物医学工程学杂志. 24(4): 829-834
16. 方颖, 凌颖琛, 向雪, 吴建华. 2008. 靶心型细胞接触面FRAP的理论数值模拟. 医用生物力学. 22(2): 185-191
17. 方颖,向雪,凌颖琛,吴建华. 2008. “细胞接触面内的扩散阻塞效应的估计”. 医用生物力学. 22(1): 30-34
18. Y. Fang, Y. Lao, Q. Li, C. Zhu and J. Wu. 2008, “A Theoretical Model for Binary Adhesion of Cells in Flows”. IFMBE Proc. 19:164-166
19. L. Liu, Y. Fang, Q. Huang, Q. Pan and J. Wu. 2008, “A New Structure-Activity Relationship of Linear Cationic α-helical Antimicrobial Peptides”, IFMBE Proc. 19:167-170
20. Y. Lao, J. Lin, Y. Fang, Q. Li, C. Zhu and J. Wu. 2008, “Numerical Simulations of Colliding Particle Distribution in Flow Chamber”. IFMBE Proc. 19:171-173
21. Fang, Y., Q. Li, C. Zhu and J. Wu. 2007. A theoretical modeling of the cell collision with bottom in flows under thermal excitation. Journal. of Medical Biomechanics, 22(S): 56-58
22. Wu, J, Y. Fang, D. Yang and C. Zhu. 2005. Thermo-mechanical Responses of a Surface-coupled AFM Cantilever. Journal. Biomechanical Engineering, ASME. 127(7):1208-1215
23. 方颖, 吴建华, 朱承. 2005. P选择子和PSGL-1之弯曲刚度的热分析方法. 中国医学物理学杂志, 22(5): 657-659, 638
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