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山东大学生命科学学院导师介绍:向凤宁


  向凤宁 教授
  博士生导师
  电话:0531-88363629
  
  教育背景:
  向凤宁,女,汉族,47岁,博士,博士生导师,2005年获得教育部新世纪优秀人才项目支持,2008年获得山东省首届杰出青年基金项目支持。“植物细胞工程与种质创新”教育部重点实验室副主任,山东省植物生理学会常务理事。2006-2007年在韩国首尔大学自然科学院植物分子信号实验室做博士后,进行拟南芥抗逆及器官发育的分子调控机制研究。
  近年来,主持国家自然科学基金、国家重大科学研究计划项目、教育部新世纪人才支持计划基金、山东省杰出青年基金、教育部博士点基金、山东省自然科学基金重点项目、山东省优秀中青年科学家科研奖励基金、山东省公关项目、山东省国际合作项目等,进行拟南芥干细胞维持与分化的分子机制;植物抗逆(盐.旱及重金属)重要基因发掘及功能研究及中药材次生代谢的分子机制等方面研究。  
  近年来,主要研究成果发表在The Plant J (SCI, IF6.948).Plant Physiology (SCI, IF6.39).Plant Cell Environment (SCI, IF5.082).Plos one (SCI, IF4.351).BMC plant biology (SCI, IF4.09).Planta (SCI, IF3.73).Plant Cell Physiology (SCI, IF3.594).T.A.G.Genome.Plant Sci..Plant cell report.Biologia Plantarum.Protoplasma.Biol. Pharm. Bull..Biosci. Biotechnol. Biochem..In vitro plant.CHROMATOGRAPHIA.Science in China.ACTA Botanica Sinica等SCI源期刊上发表论文30多篇和核心期刊(30余篇)及国际专著BAF上。2006年获得山东省自然科学奖“一等奖”;2008年获得教育部技术发明“二等奖”;2001年获山东省科技进步“二等奖”;获得8项发明专利,申请3项,其中大豆的专利3项。2005年获得教育部新世纪人才计划项目支持,2008年获得首届山东省杰出青年基金项目支持。

  教学工作:
  主讲本科生《植物生理学》、《生命科学导论》、《细胞遗传学》、《现代生物技术导论》、《植物学大实验》、《植物生物学实验》、《细胞生物学实验》等7门课,研究生的《植物生理与分子生物学》、《植物发育生物学》、《植物组织及细胞培养》、《植物细胞工程及基因工程原理与技术》、《植物遗传操作技术及原理》等5门课。曾荣获“青海省高等学校第一届青年教师讲课比赛一等奖”。在研究生的培养及本科生的毕业论文指导方面,所指导的本科生论文(2人.2次)被《山东大学本科生优秀毕业论文集》收录;所指导的硕士研究生论文被评为山东省优秀硕士论文。  
  
  研究方向:
  Ⅰ 拟南芥干细胞维持与分化的分子机制研究
  Ⅱ 植物抗逆(盐.旱及重金属)重要基因发掘及功能研究
  Ⅲ 中药材次生代谢的分子调控机制研究
  
  承担课题:
  1. 微环境调控植物生长点干细胞中心维持与重建的分子网络,国家重大科学研究计划项目,2013CB967300,2013.1-2017.12(第一位)
  2. 植物干细胞维持和分化的分子机理研究,国家重大科学研究计划项目,2007CB948203,2007.9-2011.12(第一位)
  3. 拟南芥生长素响应因子ARF10 调控离体苗再生的分子机制,国家自然科学基金,31270328,2013.1-2016.12(第一位)
  4. 拟南芥WRKY71转录因子对腋分生组织形成及侧芽发育的调控研究,国家自然科学基金,30970243,2010-2012(第一位)
  5. 金银花规范化种植基地优化升级及系列产品综合开发研究,国家科技支撑计划课题,2011BAI06B01,2012-2015(第一位)
  6. 红豆杉红豆杉 bZIP 转录因子TmbZIP1 对紫杉醇生物合成的调控机制研究,国家自然科学基金,31200226,2013.1-2015.12
  7. 红豆杉体细胞杂种紫杉醇合成基因高效表达及其等位变异研究, 国家自然科学基金,30771116,2008-2010(第一位)
  8. 高羊茅抗逆相关膜结合转录因子基因克隆及其基因工程育种研究,山东省杰出青年基金,QJ200810,2009-2011(第一位)
  9. 拟南芥WRKY7转录因子对腋分生组织形成及侧芽发育的调控研究,教育部博士点基金,913111006,2010-2012(第一位)
  10. 拟南芥转录因子 WRKY7对分枝发育的调控机制研究,山东省国际科技合作项目,2011176,2012-2014(第一位)
  11. 高寒藏药材--川西獐牙菜药效成分相关基因的转移和克隆,国家自然科学基金,30470154,2005-2007(第一位)
  12. 小麦体细胞杂交中的杂种优势及其在育种上的利用,教育部新世纪人才支持计划项目,NCET-05-0581,2006-2008(第一位)
  13. 转PcPCs/PcGCs基因富集重金属剪股颖新品种选育,山东省公关项目,2009GG10002001,2010-1012(第一位)

  研究成果及发表论文
  获奖情况:
  1. 2006年,小麦不对称体细胞杂交机制及杂种遗传和基因组研究,获山东省自然科学一等奖(夏光敏.陈惠民.向凤宁.周爱芬.支大英)。
  2. 2008年,普通小麦不对称体细胞杂交创制渐渗系育种新技术,获教育部发明二等奖(夏光敏.陈惠民.赵双宜.向凤宁)。
  3. 2001年,小麦与不同属间体细胞杂交研究,获山东省科技进步二等奖(理论成果奖)(夏光敏.周爱芬.向凤宁.陈惠民)。
  4. 2006年,小麦远缘体细胞杂交及体细胞杂种的遗传研究,被评为山东省优秀博士论文(向凤宁)
  5.2005年,指导的硕士生获得山东省优秀硕士学位论文。

  发明专利:
  1 专利名:大豆萌动胚真空渗透辅助的外源基因转化方法,完成人:向凤宁,姬丹丹,王鹏,国家发明专利,2010,授权号:ZL201010223264.5
  2.专利名:利用体细胞杂交技术将藏药材药效成分转入受体细胞的方法,完成人:向凤宁.夏光敏.蔡云飞.李子东.江莉。国家发明专利,2007,授权号:ZL200410075772.8
  3. 专利名:麻花艽β-amyrin合成酶基因GsAS1及其应用,完成人: 向凤宁,刘艳玲,国家发明专利,2009,授权号:ZL200910013892.8
  4. 专利名:川西獐牙菜香叶醇-10羟化酶基因SmG10H及其应用,完成人:向凤宁,王俊峰,国家发明专利,2009,授权号:ZL200910129803.6
  5. 专利名:麻花艽β-amyrin合成酶基因GsAS2及其应用,完成人: 向凤宁,刘艳玲,国家发明专利,2009,授权号:ZL200910013893.2
  6. 专利名: 芦苇γ-谷氨酰半胱氨酸合成酶基因PcGCS及其应用, 完成人:向凤宁,夏光敏,赵翠竹,于延冲,乔孟,国家发明专利,2007,授权号:ZL200710014450.6
  7. 专利名:一种农杆菌介导的甘薯不定芽转化方法,完成人:向凤宁,王鹏,国家发明专利,2009,授权号:ZL200910017332.X
  8. 专利名:芦苇植物络合素基因PaPCS及其应用,向凤宁 赵翠珠 赵赫,国家发明专利,2011,授权号:ZL201110189821.0
  9. 麻花艽β-amyrin合成酶基因GsAS的酵母表达产物在制药中的应用,完成人:向凤宁.赵忠娟.刘艳玲.吕欣.李朔,国家发明专利,2101,申请号:201210132433.3
  10. 专利名:大豆圣豆9号NAC转录因子基因GmST1及其应用,完成人:向凤宁,姬丹丹,李朔,国家发明专利,2012,申请号:201210128273.5
  11. 专利名:大豆圣豆9号NAC转录因子基因GmST2及其应用,完成人:向凤宁,姬丹丹,李朔,国家发明专利,2012,申请号:201210128590.7

  代表性论文:(*通讯作者)
  1. Meng Qiao, Zhongjuan Zhao, Yuguang Song, Zhenhua Liu, Lingxue Cao, Yanchong Yu, Shuo Li and Fengning Xiang*. Proper regeneration from in vitro cultured Arabidopsis thaliana requires the miRNA directed action of an auxin response factor. The Plant J. 2012. DOI: 10.1111/j.1365-313X.2012.04944.x (SCI, IF 6.948)
  2. Pil Joon Seo,1 Fengning Xiang1(co-first author), Meng Qiao, Ju-Young Park, Sang-Gyu Kim, Yong-Hwan Lee, and Chung-Mo Park. The MYB96 Transcription Factor Mediates Abscisic Acid Signaling during Drought Stress Response in Arabidopsis.Plant Physiology. 2009. 151(1):275-89. (SCI, IF 6.39)
  3. Zhao Cuizhu, Qiao Meng, Yu Yanchong, Xia Guangmin, Xiang Fengning*. The effect of the heterologous expression of Phragmites australis γ-glutamylcysteine synthetase on the Cd2+ accumulation of Agrostis palustris. Plant Cell Environment. 2010. 33: 877–887 (SCI, IF 5.082)
  4. Yuguang Song, Dandan Liu, Shuo Li and Fengning Xiang*. The dynamic changes of DNA methylation and histone modifications of salt responsive transcription factor genes in soybean. Plos One. 2012 (accepted) (SCI, IF 4.351)
  5. Junfeng Wang, Cuizhu Zhao, Chang Liu, Guangmin Xia and Fengning Xiang*. Introgression of Swertia mussotii gene into Bupleurum scorzonerifolium via somatic hybridization. BMC plant biology. 2011. 11:71-81 (SCI, IF 4.09)
  6. Fengning Xiang, Junfeng Wang, Chunhui Xu, Guangmin Xia*. The chromosome content and genotype of two wheat cell lines and of their somatic fusion product with oat. Planta. 2010. 231:1201–1210. (SCI, IF 3.372)
  7. Fangfang Zhang, Peng Wang, Guangwen Kang, Fengning Xiang*. Asymmetric protoplast fusions between Bupleurum scorzonerifolium Willd and Taxus chinensis var. mairei. Plant cell report. 2011. 30:1857–1864 (SCI, IF 2.4)
  8. Yanchong Yu, Zidong Li, Peng Wang, Fengning Xiang* Genetic and biochemical characterization of somatic hybrids between Bupleurum scorzonerifolium and Gentianopsis paludosa. Protoplasma. 2011. DOI 10.1007/s00709-011-0336-8 (SCI, IF1.52)
  9. Li Jiang, Yunfei Cai, Guangmin Xia, Fengning Xiang*. Introgression of the heterologous nuclear DNAs and efficacious compositions from Swertia tetraptera into Bupleurum scorzonerifolium Willd. via somatic hybridization. Protoplasma. 2011. DOI 10.1007/s00709 -011-0317-y (SCI, IF 1.52)
  10. Meng Qiao, Zhongjuan Zhao and Fengning Xiang*. Arabidopsis thaliana in vitro shoot regeneration is impaired by silencing of TIR1. Biologia Plantarum. 2011. DOI 10.1007/s10535-011-0233-1 (SCI, IF1.65)
  11. Wei Xin, Zhenhua Liu, Yuguang Song and Fengning Xiang*. Direct shoot regeneration from Arabidopsis thaliana shoot apical meristems. Biologia Plantarum. 2012. XX (X): XXX-XXX, 20XX (SCI, IF 1.65)
  12. Zhong-juan Zhao§, Yu-guang Song§, Yan-ling Liu§, Meng Qiao, Feng-ning Xiang*. The effect of elicitors on oleanolic acid accumulation and the expression of triterpenoid synthesis genes in Gentiana straminea. Biologia Plantarum. 2012. XX (X): XXX-XXX, 20XX (SCI, IF1.65)
  13. Junfeng Wang, Yanling Liu, Yunfei Cai, Guangmin Xia, Fengning Xiang*. Cloning and functional analysis of geraniol 10-hydroxylase, a cytochrome P450 from Swertia mussotii. Biosci.Biotechnol.Biochem. 2010. 74 (8):1583-1590 (SCI, IF1.6)
  14. Yanling Liu, Yunfei Cai, Zhongjuan Zhao, Junfeng Wang, Jing Li, Wei Xin, Guangmin Xia, Fengning Xiang*. Cloning and functional analysis of a β-amyrin synthase gene associated with oleanolic acid biosynthesis in Gentiana straminea. Biol. Pharm. Bull. 2009.32(5):818-824. Biol. Pharm. Bull. 2009. 32 (5):818-824. (SCI, IF 1.8)
  15. Cai Yunfei,Yanling Liu, Zhenhua Liu, Feng Zhang, Xiang Fengning*, Xia Guangmin. High-frequency embryogenesis and regeneration of plants with high content of gentiopicroside from the Chinese medicinal plant Gentiana straminea Maxim. In vitro plant. 2009. 45:730–739. (SCI, IF 0.7)
  16. Lihua Zang, Yanling Liu, Jiaqing Liu, Qing Tian, Fengning Xiang*. An Improved Method for Testing Weak VOCs in Dry Plants with a Purge and Trap Concentrator Coupled to GC-MS. CHROMATOGRAPHIA. 2008. 68:351-356. (SCI, IF 1.8)
  17. Pil Joon Seo, An-Kyo Lee, Fengning Xiang and Chung-Mo Park. Molecular and Functional Profiling of Arabidopsis Pathogenesis-Related Genes: Insights into Their Roles in Salt Response of Seed Germination. Plant Cell Physiology 2008. 49(3): 334–344. (SCI, IF 3.394)
  18. Jing Wang1, Fengning Xiang1 (co-first author), Guangmin Xia. Agropyron elongatum chromatin localization on the wheat chromosomes in an introgressed somatic hybrid line. Planta. 2005. 221: 277-286. (SCI, IF 3.35)
  19. Fengning Xiang, Xia Guangmin, Chen Huimin. Hybrid plant regeneration in relation to the nuclear and cytoplasmic genomes of wheat and Setaria italica. Genome. 2004. 47:680-688. (SCI, IF 2.1)
  20. Fengning Xiang, Guangmin Xia, Huimin Chen. Effect of UV dosage in somatic hybrids between common wheat and Avena sativa L. Plant Science. 2003.164:697-707. (SCI, IF 1.7)
  21. Yunfei Cai, Fengning Xiang, Daying Zhi, Guangmin Xia. Genotyping of Somatic Hybrids between Festuca arundinacea Schreb. and Triticum aestium L. Plant cell report. 2007. 26(10): 1809-1819. (SCI, IF 1.7)
  22. Guangmin Xia, Fengning Xiang, Huimin Chen. Asymmetric somatic hybridization between Triticum aestivum L. and Agropyron elongatum. T. A.G. 2003.107: 299-305. (SCI, IF 2.4)
  23. Fengning Xiang, Guangmin Xia, Humin Chen. Asymmetric Somatic Hybridization Between wheat (Triticum aestivum) and Avena sativa L. Science in China. 2003. 46 (3): 243-252(SCI)
  24. Xiang Fengning, Xia Guangmin, Chen Humin. Agronomic trait and protein component of F2 hybrid originated from intergeneric somatic hybridization between Triticum astivum and Agropyron elongatum. ACTA Botanica Sinica. 2001.43(3): 232- 237(SCI)
  25. Xiang Fengning, Xia Guangmin, Chen Huimin. Asymmetric somatic hybridization between wheat (Triticum aestivum L.) and Bromus inermis. ACTA Botanica Sinica. 1999. 41(5): 458~462. (SCI)
  26. Wang Jing, Xiang Fengning, Xia Guangmin, Chen Huimin. Transfer of small chromosome fragments of Agropyron elongatum to wheat chromosome via asymmetric somatic hybridization. Science in China. 2004. 47(5): 434-441(SCI)
  27. Xia Guangmin, Xiang Fengning, et al. Fertile thansgenic plants production from intergeneric somatic hybridization between Triticum aestivum and Agropyron elongatum. ACTA Botanica Sinica. 1999. 41(4): 428-331(SCI)
  28. Xu Chunhui, Xia Guangmin, Xiang Fengning, et al. Integration of maize nuclear and mitochondrial DNA into the wheat genome through somatic hybridization. Plant Science. 2003. 165:1001-1008. (SCI, IF 1.7)
  29. Li cuiling, Xia Guangmin, Xiang Fengning. Regeneration of asymmetric somatic hybrid plants from the fusion of two types of wheat with Russian wildrye. Plant cell report. 2004. 23: 461-467. (SCI, IF 1.4)
  30. Chen Suiyun, Xia Guangmin, Qian Taiyong, Xiang Fengning, et al. Studies on the salt-tolerance of F3-F6 hybrid Lines originated from somatic hybridization between common wheat and Thinopyrum ponticum. Plant science. 2004. 167:773-779. (SCI, IF 1.65)
  31. Xia GM, Li ZY, Xiang FN, Chen PD, Liu DJ. Asymmetric somatic hybridization between haploid common wheat and UV irradiated Haynaldia villosa. Plant Science. 1998. 137: 217-223. (SCI, IF 1.7)
  32. Li ZiDong, Shao Fei, Cai YunFei, Xiang FengNing*, Xia GuangMin. Characteristic of nuclear/cytoplasmic genomes of asymmetric somatic hybrids between Daucus carota L. var. sative Wild and Swertia musstii Franch. Journal of plant Physiology and molecular biology. 2005. 31(3): 254-260.
  33. Xia Guangmin. Xiang Fengning et al. Asymmetric somatic hybridization between Triticum aestivum L. and Leymus chinensis (Trin) Tzvel. BAF(国际专著). 2001. Vol49: 70-83

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