上海交通大学内科学专业导师介绍：吴凌云
►基本信息导师姓名：吴凌云性别：女专业名称：内科学专业代码：100201培养单位：附属第六人民医院专业领域：血液病导师类型：硕士生导师邮箱地
作者
佚名
次阅读2015-07-09
►基本信息
导师姓名：吴凌云
性别：女
专业名称：内科学
专业代码：100201
培养单位：附属第六人民医院
专业领域：血液病
导师类型：硕士生导师
邮箱地址：lincy2032@yahoo.com.cn
►研究方向
骨髓增生异常综合征发病机制及诊治
►社会任职
中华医学会上海市血液学分会委员
►科研项目
| 项目编号 | 项目名称 | 课题来源 | 起止年月 | 批准经费 | 承担职责 |
|---|---|---|---|---|---|
| 2ZR1422400 | 核糖体蛋白RPL23通过Miz1/c-Myc分子途径参RPL23在骨髓增生异常综合征发病中的作用 | 上海市自然科学基金 | 2013-01~2015-12 | 10万元 | 课题负责人 |
| 81200346 | 核糖体蛋白RPL23通过Miz1/c-Myc分子途径参与骨髓增生异常综合征发病的机制研究 | 国家自然科学基金 | 2013-01~2015-12 | 23万元 | 课题负责人 |
►学术论文
| 作者 | 论文标题 | 期刊名 | 出版年 | 卷期页码 |
|---|---|---|---|---|
| 张耀,宋陆茜,,常春康,李晓 | p15INK4B甲基化与骨髓增生异常综合征患者预后及地西他滨疗效的关系 | 中华血液学杂志 | 2013 | 34(3) :237-241 |
| Zhang X, Chang C, Zhao Y,, Zhang Z, Li X. | The effect of the combination of bisphosphonates and conventional chemotherapy on bone metabolic markers in multiple myeloma patients. | Hematology | 2012 | 17(5):255-60. |
| , Li X, Xu F, Chang C, He Q, Zhang Z, Zhang Y. | Over-expression of RPL23 in myelodysplastic syndromes is associated with apoptosis resistance of CD34(+) cells and predicts poor prognosis and distinct response to CHG chemotherapy or decitabine. | Ann Hematol. | 2012 | 91 (10):1547-1554 |
| Xu F,, He Q, Zhang Z, Chang C, Li X. | Immunophenotypic analysis of erythroid dysplasia and its diagnostic application in myelodysplastic syndromes. | Intern Med J | 2012 | 42(4):401-11. |
| Xu F, Yang R,, He Q, Zhang Z, Zhang Q, Yang Y, Guo J, Chang C, Li X. | Overexpression of BMI1 confers clonal cells resistance to apoptosis and contributes to adverse prognosis in myelodysplastic syndrome. | Cancer Lett. | 2012 | 317(1):33-40 |
| Xiao L, Qi Z, Qiusheng C, Li X, Luxi S, | The use of selective immunosuppressive therapy on myelodysplastic syndromes in targeted populations results in good response rates and avoids treatment-related disease progression. | Am J Hematol. | 2012 | 87(1):26-31. |
| Yang Y, Zhang Q, Xu F,, He Q, Li X. | Tumor suppressor gene BLU is frequently downregulated by promoter hypermethylation in myelodysplastic syndrome. | J Cancer Res Clin Oncol. | 2012 | 138(5):729-37 |
| Zhang Y,, et al. | Low RPS14 gene expression is accompanied by p53-independent apoptosis in MDS patients with 5q- aberrations. | HealthMED | 2012 | 6(7):2456-2463 |
| Xu F, Li X,, Zhang Q, Yang R, Yang Y, Zhang Z, He Q, Chang C. | Overexpression of the EZH2, RING1 and BMI1 genes is common in myelodysplastic syndromes: relation to adverse epigenetic alteration and poor prognostic scoring. | Ann Hematol. | 2011 | 90(6):643-53 |
| , Li X, Su J, He Q, Zhang X, Chang C, Pu Q. | Efficacy and safety of CHG regimen (low-dose cytarabine, homoharringtonine with G-CSF priming) as induction chemotherapy for elderly patients with high-risk MDS or AML transformed from MDS. | J Cancer Res Clin Oncol | 2011 | 137(10):1563-9. |
| Zheng Z, Feng X, Xiao L, Qianqiao Z, Qi H, | Removal of autologous activated CD4-positive T lymphocytes also results in increased colony-forming units in patients with low and intermediate-1 risk myelodysplastic syndromes. | Eur J Haematol. | 2011 | 86(1):47-56. |
| Li X, Xu F, He Q,, Zhang Z, Chang C. | Comparison of immunological abnormalities of lymphocytes in bone marrow in myelodysplastic syndrome (MDS) and aplastic anemia (AA). | Intern Med | 2010 | 49(14):1349-55. |
| Xu F, Li X,, He Q, Zhang Z, Chang C. | Flow cytometric scoring system (FCMSS) assisted diagnosis of myelodysplastic syndromes (MDS) and the biological significance of FCMSS-based immunophenotypes. | Br J Haematol | 2010 | 149(4):587-97 |
| , Li X, Su J, Chang C, He Q, Zhang X, Xu L, Song L, Pu Q. | Effect of low-dose cytarabine, homoharringtonine and granulocyte colony-stimulating factor priming regimen on patients with advanced myelodysplastic syndrome or acute myeloid leukemia transformed from myelodysplastic syndrome. | Leuk Lymphoma | 2009 | 50(9):1461-7 |
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