中科院上海药物研究所导师介绍:南发俊
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姓名:南发俊性别:男职称:研究员学历:博士电话:************-231传真:************电子邮件:fjnan@mail.shcnc.ac.cn通讯地址:上海市浦东新区郭守敬路189号201203简历:1
代表论著:
Wan-YiTai,Run-TaoZhang,Yi-mingMa,MinGu,GangLiu,JiaLi*,Fa-JunNan*Design,Synthesis,andBiologicalEvaluationofRing-OpenedBengamideAnalogues.ChemMedChem.2011,5,1555–1558
Li-FangYu,Hai-NingHu,Fa-JunNan*TotalSynthesisofLathyranoicAcidAJ.Org.Chem.,2011,76,1448–1451
Li-FangYu,Bei-YingQiu,Fa-JunNan*andJiaLi*AMPKActivatorsasNovelTherapeuticsforType2DiabetesCurrentTopicsinMedicinalChemistry,2010,10,397-410
JianbinYan,ChiZhang,MinGu,ZhiyanBai,WeiguoZhang,TiancongQi,ZhiweiCheng,WenPeng,HaibinLuo,FajunNan*,ZhaoWang*,DaoxinXie*,TheArabidopsisCORONATINEINSENSITIVE1ProteinIsaJasmonateReceptorThePlantCell,2009,21(8),2220-2236
Jean-MichelGarcia,??,AnhuiGao,Pei-LanHe,JoyceChoi,WeiTang,RobertoBruzzone,OlivierSchwartz,HugoNaya,Fa-JunNan,????,JiaLi,????,RalfAltmeyer,Jian-PingZuob,??????High-throughputscreeningusingpseudotypedlentiviralparticles:AstrategyfortheidentificationofHIV-1inhibitorsinacell-basedassayAntiviralResearch2009,81,239–247
FeiChen,An-HuiGao,JiaLi,andFa-JunNan*SynthesisandBiologicalEvaluationofC7-DemethylLargazoleAnaloguesChemMedchem,2009,4,1269-1272
Jun-QingDu,JianWu,Hua-JieZhang,Ya-HuiZhang,Bei-YingQiu,FangWu,Yi-HuaChen,Jing-YaLi,Fa-JunNan*,Jian-PingDing*andJiaLi*Isoquinoline-1,3,4-trioneDerivativesInactivateCaspase-3byGenerationofReactiveOxygenSpeciesJ.Biol.Chem.2008.283,30205-30215
ShengLiu,Yong-MeiCui,Fa-JunNan*TotalSynthesisoftheOriginallyProposedandRevisedStructuresofScleritoderminAOrg.Lett.,2008,3765-3768
Hai-JunChen,Wen-LongWang,Gui-FengWang,Li-PingShi,MingGu,Yu-DanRen,Li-FeiHou,Pei-LanHe,Feng-HuaZhu,Xian-GenZhong,WeiTang,Jian-PingZuo*,andFa-JunNan*RationalDesignandSynthesisof2,2-BisheterocycleTandemDerivativesasNovelNon-nucleosideHepatitisBVirusInhibitorsChemMedchem,2008,1316-1321
TaoPang,Z-SZhang,MinGu,Bei-yingQiu,Li-fangYu,Peng-rongCao,WeiShao,Min-boSu,Jing-yaLi,Fa-junNan*,JiaLi*.JSmallmoleculeantagonizesautoinhibitionandactivatesAMP-activatedproteinkinaseincells.J.Biol.Chem.2008,283,16051-16060
XinLi,Jian-HuaCao,YingLi,PhilippeRondard,YangZhang,PingYi,Jian-FengLiu*,Fa-JunNan*.Activity-BasedProbeforSpecificPhotoaffinityLabelingγ-AminobutyricAcidB(GABAB)ReceptorsonLivingCells:Design,Synthesis,andBiologicalEvaluationJ.Med.Chem.,2008,51,3057-3060
GangLiu,Yi-MingMa,Wan-YiTai,Chuan-MingXie,Yu-LinLi,JiaLi*andFa-JunNan*Design,Synthesis,andBiologicalEvaluationofCaprolactamModifiedBengamideAnaloguesChemMedchem,2008,3,74-78
Wen-WeiQiu,JieXu,Jing-YaLi,JiaLi,*andFa-JunNan*,Activity-BasedProteinProfilingforTypeIMethionineAminopeptidasebyUsingPhoto-AffinityTrimodularProbes,ChemBiochem,2007,1351-1358
Yi-HuaChen,Ya-HuiZhang,Hua-JieZhang,Da-ZhiLiu,MinGu,Jing-YaLi,FangWu,Xing-ZuZhu*,JiaLi*,Fa-JunNan*Design,synthesisandbiologicalevaluationofisoquinoline-1,3,4-trionederivativesaspotentcaspase-3inhibitorsJ.Med.Chem.,2006,49,1613-1623
Yihuachen,HuajieZhang,Fa-JunNan*Constructionofa3-Amino-2-pyridoneLibrarybyRing-closingMetathesisof??-Amino-acrylamideJ.Comb.Chem.2004,6,684-687
Jing-YaLi,Yong-MeiCui,Ling-LingChen,MinGu,JiaLi,Fa-JunNan*,andQi-ZhuangYe*MutationsattheS1SiteofMethionineAminopeptidasesfromEscherichiacoliandHomosapiensRevealtheResiduesCriticalforSubstrateSpecificity,J.Biol.Chem.2004.279,21128-21134
Jing-YaLi,Ling-LingChen,Yong-MeiCui,Qun-LiLuo,Fa-JunNan,*andQi-ZhuangYe*CharacterizationofFullLengthandTruncatedTypeIHumanMethionineAminopeptidaseExpressedfromEscherichiacoliBiochemistry,2004,43,7892-7898
WenglongWang,FajunNan*FirstTotalSynthesisofLeucamideAJ.Org.Chem.,2003,1636-1639
Qun-LiLuo,Jing-YaLi,Zhi-YingLiu,Ling-LingChen,JiaLi,ZhenQian,QiangShen,YuLi,Qi-ZhuangYe,*Fa-JunNan*DiscoveryandStructuralModificationofInhibitorsofMethionineAminopeptidasesfromEscherichiacoliandSaccharomycescerevisiaeJ.Med.Chem.,2003,46,2631-2640
Jing-YaLi,Ling-LingChen,Yong-MeiCui,Qun-LiLuo,JiaLi,Fa-JunNan*,Qi-ZhuangYe*Specicityforinhibitorsofmetal-substitutedmethionineaminopeptidase,BiochemicalandBiophysicalResearchCommunications2003,307,172–179
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