中科院北京基因组研究所导师介绍：吴佳妍

研究方向：
　　1）对基因组学、转录组学和表观遗传组学数据进行深度挖掘，进行以精准医疗为目的的个人基因组研究；2）延续现有原核生物泛基因组学研究成果，进行广泛的比较基因组学研究；3）发展和改进高通量测序数据深度挖掘分析方法，进行算法，并构建相应的数据库。
　　近期主要学术成果：　1.RuosiZhang,LiliHao,LingpingWang,MeiliChen,WenLi,MiguelEsteban,JunYu,JingfaXiao,JiayanWu,Geneexpressionanalysisofinducedpluripotentstemcellsfromaneuploidchromosomalsyndromes.BMCGenomics,accepted,(2013).2.ZaichaoZhang*,JiayanWu*,YongbingZhao,JingfaXiao,AsystematicstudyonGPCRprototypes:didtheyreallyevolvefromprokaryoticgenomes?IETSystemBiology,accepted,(2013).3.JiayanWu,JingfaXiao,LingpingWang,JunZhong,HongyanYin,ShuangxiuWang,ZhangZhang,JunYu,Systematicanalysisofintronsizeandabundanceparametersindiverselineages.ScienceinChinaLifeScience,accepted(2013).4.MeiliChen,JingfaXiao,JingxingLiu,ZhangZhang,JiayanWu*,JunYu*,IdentificationofHumanHKGenesandGeneExpressionRegulationStudyinCancerfromTranscriptomics.PLoSONE,8,e54082(2013).5.JiayanWu,JingfaXiao,JunYu.Latestnotableachievementsingenomics.ScienceinChina,55,645-648(2012).6.YanGe*,JiayanWu*,MingYang,YingjieXia,JingfaXiao,JunYu,MolecularDynamicsSimulationoftheComplexPBP-2xwithDrugCefuroximetoExploretheDrugResistanceMechanismofStreptococcussuisR61.PLoSONE,6,e35941(2012).7.DongyuZhao*,JiayanWu*,WeiGong,YuanyuanZhou,JingJin,JingfaXiao,JunYu,WikiCell:aunifiedresourceplatformforhumantranscriptomicsresearch.OMICS:AJournalofIntegrativeBiology,16(6)357-362(2012).8.YongbingZhao*,JiayanWu*,JunhuiYang,ShixiangSun,JingfaXiao,JunYu,PGAP:Pan-GenomesAnalysisPipeline.Bioinformatics,28,416-418(2012).9.YanGe*,JiayanWu,*JingfaXiao,JunYu,Explorationofthebindingmodeofα/β-typesmallacidsolubleproteins(SASPs)withDNA.JournalofMolecularModeling,Vol.17,3183-3193(2011).10.JiayanWu?,JingfaXiao?,RuosiZhang,JunYu.DNAsequencingleadstogenomicsprogressinChina.ScienceinChina,54,290-292(2011).11.JingdeBu?,JiayanWu?,MeiliChen,JingfaXiao,JunYu,XuebinChi,ZhongJin.BAsplice:Bi-directionAlignmentfordetectingsplicejunctions.2012IEEE6thInternationalConferenceonSystemsBiology(ISB),Xian,China,August18-20,pp.253-256(2012).12.ZunmingLiu,JingfaXiao,JiayanWu*,JunYu*,RNADAP-RNA-SeqDataAnnotationPipeline.IEEEISB2011,Zhuhai,China,84-86(2011).13.ZaichaoZhang?,JiayanWu?,JunYu,JingfaXiao.AbriefreviewontheevolutionofGPCR:conservationanddiversification.OpenJournalofGenetics,2,11-17(2012).14.EwanBirney,ThomasJHudson,EricDGreen,…,JiayanWu,JunYu,Prepublicationdatasharing.Nature,461(7261),168-170(2009)