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浙江大学机械工程学系导师介绍:苟中入


  姓名:苟中入
  性别:男
  所在学院:材料科学与工程学系
  职称:副研究员

  个人简介
  副研究员,硕士生导师,中国生物材料学会会员,Journal of Nanoscience Letters杂志Editorial Board Member; 入选2011年度浙江省“151人才工程”培养对象。
  1995.09~1999.07 中南工业大学 工学学士
  1999.09~2002.02 中南大学 工学硕士
  2002.03~2005.03 中科院上海硅酸盐研究所 工学博士
  2005.03~2007.04 浙江大学 博士后
  2007.05~ 浙江加州国际纳米技术研究院 副研究员

  主要从事骨科、口腔科、眼科和创伤科生物医用纳米材料及细胞生物学、纳米营养学、防护纳米材料等研究,先后主持国家自然基金(青年基金)、浙江省科技厅面上(重点)项目、浙江省自然基金、浙江省教育厅、浙江省科技厅公益性项目等,参与国家自然基金重点项目(子课题)、市-校合作项目、绍兴市公益基金等合作项目5项;提出多元生物活性物质协同组装纳米材料和跨尺度纳米材料的设计,并初步解决了骨再生修复材料设计中多元生物活性物质协同管理和控制释放的难题,研发低成本制造多维微量营养素功能饮品,在国际刊物J Phys Chem C, J Mater Chem, J Biomed Mater Res (A, B)、Acta Biomater, J Controlled Release等发表学术论文30篇,申请发明和实用新型专利20项(获授权专利11项)。

  工作研究领域
  1.生物材料与再生医学(包括骨科、口腔科、眼科和创伤科组织损伤再生修复微创可注射材料、 高强度多孔生物活性材料、仿生涂层材料等)
  2.纳米营养学(多维营养保健纳米技术、纳米生物安全性等)3.防护技术(包括纳米纤维膜阻隔材料、空气净化纳米纤维膜材料)

  工作研究项目:
  浙江省科技厅面上科研项目: 骨质疏松性骨折微创治疗生物诱导活性纳米材料的研制(2008C21058), 2008.01~2009.12.
  温州市-浙江大学市校合作科研项目: 注射型原位诱导骨折愈合生物纳米材料的设计与研制(H20080039), 2009.01~2011.12.
  国家自然科学基金: 仿生凝胶体系中多元微量元素对类骨矿物介导作用的基础研究(50902121), 2010.01~2012.12.
  浙江省自然科学基金: 多孔生物玻璃材料力学增强机制及原位骨再生基础研究(Y4090029), 2010.01~ 2011.12;
  浙江省教育厅科研计划项目:促糖尿病足溃疡愈合仿生纳米纤维海绵材料的性能研究(2010SSA005)2011.01~2012.12

  发表论文:
  部分学术论文:
  Wang C, Shi X, Chen X, Wu H, Zhang H, Xie J, Yang X, Gou Z, Ye J*. 17-β-estradiol inhibits hyperosmolarity-induced proinflammatory cytokine elevation via the p38 MAPK pathway in human corneal epithelial cells. Mol Vision. 2012; 18:1115-1122.
  Zhang G, Huang R, Li Z, Chen X, Yang X, Sun X, Yang G, Gao C, Xia W, Gou Z*. Understanding the influence of alendronate on the morphology and phase transformation of apatitic precursor nanocrystals. J Inorg Biochem. 2012; 113; 1-8.
  Dan Li, Chen Ye, Yang Zhu, Gou Z, Gao C*. Enhancement of osteogenesis by poly(lactide-co-glycolide) sponges loaded with surface-embedded hydroxyapatite particles and rhBMP-2. J Biomed Maters Res. Part B. 2012: 100B: 1103-1113.
  Yang X, Zhang L, Chen X, Sun X, Yang G, Guo X, Zhang Q, Yang H, Gao C, Gou Z*. Influence of B2O3 on the thermal and bioactive properties of CaO-SiO2-P2O5 system. J Non-Crystal Solids. 2012; 358: 1171– 1179.
  Yang G, Yang X, Li Z, Lin M, Sun X, Chen X, Gou Z* Counterionic biopolymers-reinforced bioactive glass scaffolds with improved mechanical properties in wet state. Mater Lett. 2012; 75:80-83
  Yang X, Zhang L, Chen X, Yang G, Gao C, Zhang X, Zhang L, Yang H, Gou Z*. Trace elements-incorporating octacalcium phosphate porous beads via polypeptide-assisted nanocrystals self-assembly for potential applications in osteogenesis. Acta Biomater. 2012; 8: 1586-1596.
  Li D, Wang W, Guo R, Qi Y, Gou Z, Gao C*. Restoration of rat calvarial defects by poly(lactide-co-glycolide)/ hydroxyapatite scaffolds loaded with bone mesenchymal stem cells and DNA complexes. Chin Sci Bulliton. 2012; 57: 435-444.
  Xu S, Yang X, Chen X, Lin X, Zhang L, Yang G, Gao C, Gou Z*. Hybrid calcium phosphate coatings with the addition of trace elements and polyaspartic acid by a low-thermal process. Biomed. Mater. 2011; 6: 035002.
  Su P, Wang C, Yang X, Chen X, Gao C, Feng X.-X., Chen J.-Y., Ye J, Gou Z*. Elelctrospinning of chitosan nanofibers: The favorable effect of metal ions. Carbohydtrate Polymers. 2011;84: 239-246.
  Wang J, Gao X, Yang X, Gan Y, Zhang X, Gou Z*. A facile pollutant-free approach toward a series of nutritionally effective calcium phosphate nanomaterials for food and drink additives. J. Nanopart. Res. 2011; 13: 1039-1048.
  Yang X, Gao X, Gan Y, Zhao L, Gao C, Zhang X, Feng Y, Ting K, Gou Z*. Preparation and characterization of trace elements-multidoped injectable biomimetic materials for minimally invasive treatment of osteoporotic bone trauma. J. Biomed. Mater. Res. Part A. 2010;95A:1170-1181. (featured as front cover of the issue).
  Ye J*, Wang C., Su P., Wu H., Zhou Y., Yao K., Yang J., Gou Z*. Biochemically active hydrosol as a means of collecting electrospun microcapsules for drug delivery. J. Mater. Chem. 2010; 20: 9025-9028. (*Co-corresponding author).
  Yang X, Gao X, Gan Y, Gao C, Zhang X, Ting K, Wu MB, Gou Z*. Facile Synthesis of octacalcium phosphate nanobelts: growth mechanism and surface adsorption properties. J Phys Chem C, 2010; 114: 6265- 6271.
  Wang J, Gao X, Yang X, Gan Y, Weng W, Gou Z*. A facile strategy for in situ core-template-functionalizing siliceous hollow nanospheres for guest species entrapment. Nanoscale Res Lett. 2009; 4: 1171-1177.
  Gou Z*, Yang X, Gao X, Zhang X, Ting K, Octacalcium phosphate microscopic superstructure self-assembly and evolution by dual-mediating combination. CrystEngComm. 2009; 11: 1585-1590.
  Gou Z, Weng W*, Han G, Yan W. Tailoring of multilayered core-shell nanostructure for multicomponents administration and controllable release of biologically active ions. J Biomed Maters Res. Part A, 2008; 85A: 909-918.
  Feng J*, Yan W, Gou Z, Weng W, YangD. Stimulating effect of silica-containing nanospheres on proliferation of osteoblast-like cells. J Mater Sci: Mater Med. 2007; 18; 2167-2172.
  Gou Z, Weng W*, Yan W, Du P, Han G. A novel route to fabricate the biomedical material: structure strategy and the biologically active ions controllable release. J. Controlled Release. 2006; 116: 360-364.
  Gou Z, Weng W*, Han G. An efficient ultrasound-enhanced controllable release of biologically active trace elements on bioactive silica-gel -based material. Chem Lett. 2006; 35: 1214-1215.
  Gou Z, Weng W*. Effect of sodium phosphate and calcium nitrate on gelation, particle size, and texture of sol-gel-derived silica in vitro. Key Eng Mater. 2006; 330: 203-207.

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