扬州大学兽医学院导师介绍:孙怀昌
教师姓名: 孙怀昌 性 别: 男 籍 贯: 江苏涟水 出生年月: 1956.7 职 称: 教 授 最
教师姓名: 孙怀昌
性 别: 男
籍 贯: 江苏涟水
出生年月: 1956.7
职 称: 教 授
最高学历: 博士研究生
个人简历:
1982年毕业于原江苏农学院兽医专 业;1982-1987年为江苏农学院畜牧兽医系助教,从事兽医微生物学及免疫学的教学和科研,1987年晋升讲师;1990年在英国Surrey大学进 修分子生物学,从事抗体基因工程研究;1991年起在英国动物健康研究所攻读博士学位,从事非洲猪瘟病毒分子生物及免疫学研究,1995 年获分子病毒学博士学位;1995 年起为美国宾夕法尼亚大学博士后,从事遗传疾病的基因治疗研究;1998 年回扬州大学任教。现为扬州大学兽医学院专业主任,江苏省转基因动物制药工程研究中心主任,兽医微生物学与免疫学教研组组长,扬州大学预防兽医学国家级重 点学科、教育部新型疫苗工程中心、江苏省动物预防医学重点实验室、江苏省人兽共患病学重点实验室带头人之一,扬州大学动物学重点学科带头人,国家教育部骨 干教师,江苏省普通高校“青蓝工程”新世纪学术带头人,江苏省生物技术学会副秘书长,中国实验动物学会、江苏省畜牧兽医学会、中国免疫学会会员,《中国生 物工程杂志》评审专家,《中华医药杂志》常务编委,《中华医学实践杂志》常务编委,《基因工程原理与应用》编委,《基因工程实验技术》副主编。兼任江苏省 政协委员,扬州市政协常委,九三学社江苏省委常委,九三学社扬州市委员会主委等社会职务。
研究方向和领域:
兽医微生物学及免疫学;转基因动物及实验动物在疫病控制中的应用;生物制药及其产业化开发
代表性论著(限 20 篇):
[1] Huaichang Sun, Susan C. Jacobs, Geoffrey L. Smith, Linda K. Dixon and R.E.M. Parkhouse. African swine fever virus gene j13L encodes a 25~27 kDa virion protein with variable numbers of amino acid repeats. Journal of General Virology. 1995,76:1117-1127.
[2] H. Sun. Characterization of immune responses to African swine fever virus-encoded antigens. British Library. 1995.
[3] Huaichang Sun, Jessica Jenson, Linda K. Dixon and R.Michael E. Parkhouse. Characterization of the African swine fever virus virion protein j18L. Journal of General Virology. 1996,77:941-946.
[4] HUAICHANG SUN, MARK E. HASKINS, DONNALD F. PATTERSON and JOHN H. WOLFE. Expression and secretion of high levels of human lysosomal alpha-mannosidase after gene transfer into mannosidosis cells. American Journal of Human Genetics. 1997.
[5] S.M. Brookes, H. Sun, L .K. Dixon and R.M.E. Parkhouse. Characterization of African swine fever virion proteins j5R and j13L: immuno-localization in virus particles and assembly sites. Journal of General Virology. 1998,79: 1179-1188.
[6] HUAICHANG SUN, MING YANG, MARK E. HASKINS, DONNALD F. PATTERSON and JOHN H. WOLFE. Retrovirus vector mediated correction and cross-correction of lysosomal alpha-mannosidase deficiency in human and feline fibroblasts. Human Gene Therapy. 1999,10: 1311-1319.
[7] Huaichang Sun and John H. Wolfe. Characterization of an unusual variant mRNA of human lysosomal alpha-mannosidase. Experimental and molecular Medicine. 2000.
[8] Huaichang Sun and John H. Wolfe. Recent progress in lysosomal α-mannosidase and its deficiency. Experimental and Molecular Medicine. 2001, 33(1): 1-7.
[9] Huaichang Sun, Lei Zhang, Anping Wang and Zhengfeng Xue. Prolonged Hypotensive Effect of Human Tissue Kallikrein Gene Delivery and Recombinant Enzyme Administration in Spontaneous Hypertension Rats. Experimental and molecular Medicine. 2004,36(1): 23-27.
[10] Gao Bo, SUN Huai-chang, SONG Cheng-yi, WANG Zhi-yue, CHENG Qin, SONG Hong-qin. Transfection and expression of exogenous gene in laying hens oviduct in vitro and in vivo. Journal of Zhejiang University Science SCIENCE. 2005,6B(2):137-141.
[11] Darong Cheng, Huaichang Sun, Jiansheng Xu, Song Gao. Prevalence of fimbial colonization factors F18ab and F18ac in Escherichia coli isolates from weaned piglets with edema and/or diarrhea in China. Veterinary Microbiology. 2005, 110: 35-39.
[12] SUN Huai-chang, XUE Fang-ming, QIAN Ke, FANG Hao-xia, QIU Hua-lei, ZHANG Xin-yu, YIN Zhao-hua. Intramammary expression and therapeutic effect of a human lysozyme-expressing vector for treating bovine mastitis. Journal of Zhejiang University Science SCIENCE B. 2006, 7(4): 324-330.
[13] Gao B, Sun HC, Fang HX, Qian K, Zhao MS, Qiu HL, Song CY, Wang ZY. Expression and preliminary characterization of recombinant human tissue kallikrein in egg white of laying hens. Poultry Science. 2006, 85(7): 1239-1244.
[14] Cheng D, Sun H, Xu J, Gao S. PCR detection of virulence factor genes in Escherichia coli isolates from weaned piglets with edema disease and/or diarrhea in China. Vet Microbiol. 2006.115(4):320-8.
[15] WANG An-ping, SUN Huai-chang, WANG Jian-ye, WANG Yong-juan and YUAN Wei-feng. The helper activities of different avian viruses for propagation of recombinant avian adeno-associated virus. Scientia Agricultura Sinica. 2007.
[16] A. P. Wang, H. C. Sun, J. Y. Wang, Y. J. Wang, W. F. Yuan. Recombinant avian adeno-associated virus-mediated oviduct-specific expression of recombinant human tissue kallikrein. Poultry Science. 2008.
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