南通大学神经科学系导师介绍：王勇军

　　王勇军，1967年12月出生，理学博士，教授，硕士研究生导师。省“333”第三层次培养对象，江苏省“六大人才高峰”B类资助对象。主要研究方向为神经再生分子生物学以及分子发育生物学。

　　主持国家自然基金2项，江苏省高校基础研究重大项目1项等。获教育部自然科学二等奖（排名5）1项。共发表SCI 40余篇。

　　主要科研工作：

　　1．以爬行动物多疣壁虎为实验动物，研究壁虎断尾再生过程中芽基细胞位置记忆产生以及神经元轴突再生的分子基础，揭示芽基细胞位置识别以及神经元轴突再生的相 关分子机制；研究炎症因子在自发性脊髓再生过程的功能转换以及对神经再生的影响，从免疫学角度寻找免疫相关因子和中枢神经再生之间的关系。

　　2．胚胎发育相关基因的进化及功能研究。采用系统分析，比较不同物种中该基因的进化关系，通过发育相关基因的表达图式，研究、推断其发育或再生中的功能，为中枢神经再生提供分子生物学线索。

　　近5年发表的文章：

　　1．Yingying Dong, Yun Gu, Youjuan Huan, Yingjie Wang, Yan Liu, Mei Liu, Fei Ding, Xiaosong Gu, Yongjun Wang．HMGB1 does not mediate the inflammatory response in spontaneous spinal cord regeneration: A hint for CNS regeneration．J Biol Chem, 2013, 288: 18204–18218．

　　2．Yu B, Qian T, Wang Y, Zhou S, Ding G, Ding F, Gu X．miR-182 inhibits Schwann cell proliferation and migration by targeting FGF9 and NTM, respectively at an early stage following sciatic nerve injury．Nucleic Acids Res．2012, 40: 10356-10365．

　　3．Yingjie Wang, Yingying Dong, Honghua Song, Yan Liu, Mei Liu, Ying Yuan, Fei Ding, Xiaosong Gu, Yongjun Wang．Involvement of gecko SNAP25b in spinal cord regeneration by promoting outgrowth and elongation of neurites．Int J Biochem CellB．2012, 44:2288-2298．

　　4．Yongjun Wang, Xin Tang, Bin Yu, Yun Gu, Ying Yuan, Dengbing Yao, Fei Ding, Xiaosong Gu．Gene network revealed involvements of Birc2, Birc3 and Tnfrsf1a in anti-apoptosis of injured peripheral nerves．Plos one．2012,7(9):e43436．

　　5．Bin Yu, Songlin Zhou, Yongjun Wang, Tianmei Qian, Guohui Ding, Fei Ding, and Xiaosong Gu．miR-221/222 promote Schwann cell proliferation and migration by targeting LASS2 following sciatic nerve injury．J Cell Sci．2012, 125: 2675-2683．

　　6．Yingjie Wang, Qing Gu, Yingying Dong, Weijuan Zhou, Honghua Song, Yan Liu, Mei Liu, Ying Yuan, Fei Ding, Xiaosong Gu, Yongjun Wang．Inhibition of gecko GSK-3β promotes elongation of neurites and oligodendrocyte processes but decreases the proliferation of blastemal cells．J cell biochem．2012,113:1842-1851．

　　7．Yongjun Wang, Ruili Wang, Shengjuan Jiang, Weijuan Zhou, Yan Liu, Yingjie Wang, Qing Gu, Yun Gu, Yingying Dong, Mei Liu, Xingxing Gu, Fei Ding, Xiaosong Gu．Gecko CD59 is implicated in proximodistal identity during tail regeneration．Plos one．2011, 6:e17878．

　　8．Yongjun Wang, Xiaoxia Jiang, Yan Liu, Xingxing Gu, Youjuan Huan, Lijie Ren, Fei Ding, Xiaosong Gu．Molecular cloning and altered expression of Pbx4 in the spinal cord during tail regeneration of Gekko japonicus．Brain Res Bull．2009, 80: 414–421．

　　9．Wang YJ, Zhao BS, Ding F, Jiang XX．Gut-specific expression of Cathepsin L and B in amphioxus Branchiostoma belcheri tsingtauense．Eur J Cell Biol．2008, 87: 185–193．

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