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南京医科大学药学院导师介绍:陈芸


  陈芸,博士
  地址:南京市汉中路140号药学院
  邮编:210029
  电话:************
  E-mail: ychen@njmu.edu.cn
  陈芸,2000年获南京大学化学学士学位,同年保送南京大学分析化学专业,2002年获硕士学位。7月赴美国明尼苏 达大学(University of Minnesota, UMN)攻读博士学位,主要从事抗肿瘤药物的分子作用机理研究。2006年12月获生物分析化学博士学位。同年10月,赴美国Charles River实验室工作,主要研究方向是新药的临床药代动力学。2008年9月回国,进入南京医科大学工作,担任药学院临床药学专业教授。

  研究兴趣:
  (1) 亚细胞药代动力学,(2)抗肿瘤药物的分子作用机制,(3)临床蛋白组学和基因组学。

  主要发表论文如下:

  • Chen, Y.; Qiao, S.; Wang, X.; Liu, Y., "An investigation into fragmentation of hEGF in triple quadrupole mass spectrometry and its quantitative application to human plasma". International Journal of Mass Spectrometry, 2010, 295: 7-12.
  • Chen, Y.; Pei. J., “Factors influencing the association between CYP17 T34C polymorphism and the risk of breast cancer: meta-regression and subgroup analysis”. Breast Cancer Research and Treatment, 2010, 122, 471-81.
  • Chen, Y.; Qiao, S.; Wang, C., “Fragmentation of Peptides with Intra-Chain Disulfide Bonds in Triple Quadrupole Mass Spectrometry and its Quantitative Application to Biological Samples.” International Journal of Mass Spectrometry, 2009, 288, 68-74
  • Chen, Y.; Pei. J., “An Assessment of a TNF Polymorphic Marker for the Risk of HCV Infection: Meta-analysis and a New Clinical Study Design”. Infection, Genetics and Evolution, 2009, 9, 1356-63.
  • Chen, Y.; Liu, Y.; Wang, C., “Utilization of Immonium Product Ions for the Determination of Peptide Drugs with Intra-loops in Biological Matrices”. Analytical Letters , 2009, 42, 3004-3017.
  • Chen, Y.; Arriaga, E. A., “Individual Electrophoretic Mobilities of Liposomes and Acidic Organelles Displaying pH Gradients Across Their Membranes”. Langmuir, 2007, 23, 5584-90.
  • Chen, Y.; Xiong, G.; Arriaga, E. A., “CE analysis of the acidic organelles of a single cell”. Electrophoresis, 2007, 28, 2406-15.
  • Chen, Y.; Arriaga, E. A., “Individual Acidic Organelle pH Measurements by Capillary Electrophoresis”, Analytical Chemistry, 2006, 78, 820-826.
  • Chen, Y.; Walsh, R. J.; Arriaga, E. A., “Individual Organelle Analysis for Selective Determination of the Doxorubicin Content of Acidic Organelles in Impure Subcellular Fractions”, Analytical Chemistry, 2005, 77, 2281-2287.
  • Xiong, G.; Chen, Y.; Arriaga, E. A., “Measuring the Doxorubicin Content of Single Nuclei by Micellar Electrokinetic Capillary Chromatography with Laser-Induced Fluorescence Detection”, Analytical Chemistry, 2005, 77, 3488-3493.
  • Liu, S; Chen. Y.; Chen. H., “Studies of Spectroscopy and Cyclic Voltammetry on a Zirconium Hexacyanoferrate Modified Electrode”. Journal of Electroanalytical Chemistry, 2001, 502, 197-203.
  • Liu, S; Chen, Y.; Chen. H., “Electrochemical Studies on a Zirconium Hexacyanoferrate Modified Electrode and Utility for the Determination of Rubidium.” Electroanalysis, 2001, 14, 116-121.

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