江西师范大学化学化工学院导师介绍：万结平

　　研究方向：有机合成，药物合成

　　联系方式：wanjieping@jxnu.edu.cn；wanjieping@126.com

　　简介：

　　万结平，副教授，男。江西人，2005年至2010年在浙江大学化学系潘远江教授课题组攻读博士研究生，2010年6月获理学博士学位。主要从事高效合成方法学以及生物活性有机小分子合成方面的研究，包括多组分合成以及过渡金属催化等。在国际知名期刊Journal of American Chemical Society, Chemical Communications, Journal ofOrganic Chemistry, Chemistry-an Asian Journal, Green Chemistry, Tetrahedron, Synlett等发表研究论文多篇。曾获得荣誉称号和奖学金包括东港博士生奖学金，赢创奖学金(德国赢创-德固赛公司)，浙江大学三好研究生，浙江大学优秀毕业生，浙江省优秀毕业生等。2010年被国家自然科学基金委中德科学中心选拔为全国30名博士研究生之一，代表中国博士生参加了德国林岛60届诺贝尔奖获得者大会。2010年7月进入江西师范大学化学化工学院工作，独立工作以来已发表或接SCI收论文近20篇。2011年9月赴德国亚琛工业大学有机化学研究所Dieter Enders教授课题组进行博士后研究，2012年8月回国。目前主持国家自然科学基金一项，江西省自然科学基金一项，2012年获江西师范大学首批青年英才计划项目。受邀担任Synlett, Green Chemistry, Chemical Reviews等多个国际化学期刊审稿人。

　　目前，课题组研究工作正全面开展，欢迎有志于从事有机合成研究和应用探索的同学加入课题组！

　　在研项目：

　　国家自然科学基金青年基金 (2012.01-2014.12，主持，no. 21102059，25万)

　　国家自然科学基金委中德科学中心林岛青年学者计划(2011.09-2012.08, no. GZ710，合作教授为著名有机化学家亚琛工业大学Dieter Enders教授)

　　江西省自然科学基金青年基金 (2012.01-2014.12，no. 20114BAB213005, 1.5万)

　　江西师范大学青年英才计划项目(2012.01-2014.12，9万)

　　江西师范大学博士启动基金 (2010.10-2013.09，主持，2万)

　　江西师范大学青年成长基金 (2012.01-2014.12，主持人，0.5万)

　　发表论文(部分)

　　到江西师大工作之后发表论文：

　　[1] Jie-Ping Wan, Charles C. J. Loh, Fangfang Pan, Dieter Enders.* Enantioselective Orgnanocatalytic Domino Synthesis of Tetrahydropyridin-2-ols. Chemical Communications 2012, 48, 10049-10051.

　　[2] Jie-Ping Wan,* Chunping Wang, Yunyun Liu. Chemo-selective copper-catalyzed C-O coupling reactions of phenols with aryl/vinyl halides using enaminone as efficient ligand. Applied Organometallic Chemistry 2012, 26, 445-447.

　　[3] Jie-Ping Wan,* Yunyun Liu. Recent advances in new multicomponent synthesis of structurally diversified 1,4-dihydropyridines. RSC Advances 2012, 2, 9763-9771. (Invited review paper)

　　[4] Jie-Ping Wan, Chunping Wang, Rihui Zhou, Yunyun Liu.* Sustainable H2O/ethyl lactate system for ligand-free Suzuki–Miyaura reaction. RSC Advances 2012, 2, 8789-8792.

　　[5] Jie-Ping Wan, Yuanjiang Pan,* Recent advance in the pharmacology of dihydropyrimidinone. Mini-Reviews in Medicinal Chemistry, 2012, 12, 337-349. (Invited review paper)

　　[6] Jie-Ping Wan,* Rihui Zhou, Yunyun Liu, Mingzhong Cai. A “byproduct–intermediate–product” recycling strategy for multicomponent synthesis of 1,4-dihydropyridines. RSC Advances, 2013, 3, 2477-2482.

　　[7] Yunyun Liu, Rihui Zhou, Jie-Ping Wan.* Water promoted synthesis of enaminones, mechanism investigation and application in multicomponent reactions. Synthetic Communications 2013, DOI: 10.1080/00397911.2012.715712.

　　[8] Yunyun Liu, Hang Wang, Jie-Ping Wan.* Recent advances in diversity oriented synthesis through isatin-based multicomponent reactions. Asian Journal of Organic Chemistry, 2013, in press, DOI: 10.1002/ajoc.201200180. (Invited review paper)

　　[9] Yunyun Liu, Jie-Ping Wan.* Advances in Copper-Catalyzed C–C Coupling Reactions and Related Domino Reactions Based on Active Methylene Compounds. Chemistry-An Asian Journal. 2012, 7, 1488-1501.

　　[10] Jie-Ping Wan,* Chunping Wang, Yunyun Liu. Direct Synthesis of Enaminone Functionalized Biaryl Ethers by CuI-Catalyzed O-Arylation of Enaminone Functionalized Phenols. Organic & Biomolecular Chemistry 2011, 9, 6481-6483.

　　[11] Jie-Ping Wan,* Yunyun Liu. Multicomponent Reactions Promoted by Organosilicon Reagents. Current Organic Chemistry 2011, 15, 2758-2773.

　　[12] Jie-Ping Wan,* Yunyun Liu. Synthesis of Dihydropyrimidinones and Thiones by Multicomponent Reactions: Strategies Beyond the Classical Biginelli Reaction. Synthesis 2010, 3943-3953.

　　[13] Jie-Ping Wan, Chunping Wang, Yuanjiang Pan.* Novel Four-component Reaction Towards Diastereoselective Synthesis of Tetrahydropyrimidinthiones. Tetrahedron 2011, 67, 922-926.

　　[14] Runsheng Xu, Jie-Ping Wan, Hui Mao, Yuanjiang Pan*.Facile Synthesis of 2-(Phenylthio)phenols by Copper(I)-Catalyzed Tandem Transformation of C-S Coupling/C-H Functionalization. Journal of the American Chemical Society 2010, 132, 15531-15533.

　　[15] Shi-Feng Gan, Jie-Ping Wan, Yuan-Jiang Pan, Cui-Rong Sun. Highly Efficient and Catalyst-Free Synthesis of Substituted Thioureas in Water. Molecular Diversity 2011, 15, 809-815.

　　[16] Yunyun Liu, Jie-Ping Wan. Tandem Reactions Initiated By Copper-Catalyzed Cross-Coupling: A New Strategy Towards Heterocycle Synthesis. Organic & Biomolecular Chemistry 2011, 9, 6873-6894.

　　[17] Cheng Guo, Jieping Wan, Nan Hu, Kezhi Jiang, Yuanjiang Pan*. An Experimental and Computational Investigation on the Fragmentation Behavior of Enaminones in Electrospray Ionization Mass Spectrometry. Journal of Mass Spectrometry 2010, 45, 1291-1298.

　　[18] Hui Mao, Runsheng Xu, Jie-Ping Wan, Yuanjiang Pan*. Tunable Hydride Transfer in the Redox Amination of Indoline with Aldehyde: An Attractive Intramolecular Hydrogen Bond Effect. Chemistry-A European Journal. 2010, 16, 13352-13355.

　　参加工作之前发表论文：

　　[1] Jie-Ping Wan, Yuan-Jiang Pan*. Chemo-/Regioselective Synthesis of 6-Unsubstituted Dihydropyrimidinones, 1,3-Thiazines and Chromones via Novel Variants of Biginelli Reaction. Chemical Communications 2009, 2768-2770.

　　[2] Jie-Ping Wan, Shi-Feng Gan, Gong-Lei Sun, Yuan-Jiang Pan*. Novel Regioselectivity: Three-component Cascade Synthesis of Unsymmetrical 1,4- and 1,2-Dihydropyridines. Journal of Organic Chemistry 2009, 74, 2862-2865.

　　[3] Jie-Ping Wan, Shi-Feng Gan, Jian-Mei Wu, Yuanjiang Pan*. Water Mediated Chemoselective Synthesis of 1,2-Disubstituted Benzimidazoles using o-Phenylenediamine and the Extended Synthesis of Quinoxalines. Green Chemistry 200911, 1633-1637.

　　[4] Jie-Ping Wan, Jing Zhou, Hui Mao, Yuan-Jiang Pan*, An-Xin Wu. A New Diastereoselective Multicomponent, One-pot Strategy for the Synthesis of 3-Substituted Isoindolinones via Efficient C–C Bond Formation. Tetrahedron 2008, 64, 11115-11123.

　　[5] Jieping Wan, Bin Wu, Yuanjiang Pan*. Novel One-step Synthesis of 2-Carbonyl/Thiocarbonyl Isoindolinones and Mechanistic Disclosure on the Rearrangement Reaction of o-Phthalaldehyde with Smide/Thioamide Analogs. Tetrahedron 2007, 63, 9338-9344.

　　[6] Jie-Ping Wan, Yun-Feng Chai, Jian-Mei Wu, Yuan-Jiang Pan*. N,N'-(Phenylmethylene)diacetamide Analogues as Economical and Efficient Ligands in Copper-Catalyzed Arylation of Aromatic Nitrogen-containing Heterocycles. Synlett 2008, 3068-3072.

　　[7] Jie-Ping Wan, Yuan-Hang Pan, Hui Mao, Yun-Hua Chen, Yuan-Jiang Pan*. Microwave Assisted Three-component Reaction for Rapid Synthesis of Some 5,6-Dihydro-4H-1,3-thiazine Derivatives Under Solvent-Free Condition. Synthetic Communications 2010, 40, 709-716.

　　[8] Chunyan Wang, Jieping Wan, Zhiguo Zheng, Yuanjiang Pan*. A New InCl3-Catalyzed Reduction of Anthrones and Anthraquinones by Using Aluminum Powder in Aqueous media. Tetrahedron 2007, 63, 5071-5075.

　　[9] Hui Mao, Jieping Wan, Yuanjiang Pan*. Facile and Diastereoselective Synthesis of β-Acetamido Ketones and Keto Esters via Direct Mannich-type Reaction. Tetrahedron 2009, 65, 1026-1032.

　　[10] Hui Mao, Jie-Ping Wan, Yuanjiang Pan*. Synthesis of 2-Substituted Indoles via a Palladium-Catalyzed Domino Heck Reaction and Dealkylation. Tetrahedron Letters 2010, 51, 1844-1846.

　　[11] Shi-Feng Gan, Jie-Ping Wan, Yuan-Jiang Pan, Cui-Rong Sun*. Water-Mediated Multicomponent Reaction: A Facile and Efficient Synthesis of Multisubstituted Thiazolidine-2-thiones. Synlett 2010, 973-975.

　　[12] Yunhua Chen, Jieping Wan, Chunyan Wang, Cuirong Sun*. Diastereoselective Synthesis of Cyclopentanediols by InCl3/Al Mediated Intramolecular Pinacol Coupling Reaction in Aqueous Media. Molecules 2008, 13, 2652-2658.

　　[13] Jianmei Wu, Jieping Wan, Cuirong Sun*. Crystal Structure and Mass Spectrometric Fragmentation Behavior of Eprosartan. Chinese Journal of Structural Chemistry 2009, 28, 1087-1092.

　　[14] Yulin Zhu, Shenlin Huang, Jieping Wan, Lei Yan, Yuanjiang Pan, Anxin Wu. Two Novel Diastereoselective Three-component Reactions of Alkenes or 3,4-Dihydro-(2H)-pyran with Urea/Tthiourea-Aldehyde Mixtures: [4+2] Cycloaddition vs Biginelli-Type Reaction. Organic Letters 2006, 8, 2599-2602.

　　[15] Yunfeng Chai, Hezhi Sun, Jieping Wan, Yuanjiang Pan, Cuirong Sun. Hydride

　　Abstraction in Positive-ion Electrospray Interface: Oxidation of 1,4-Dihydropyridines in Electrospray Ionization Mass Spectrometry. Analyst 2011, 136, 4667-4669.

　　[16] Yaqin Liu, Lihui Zhang, Jieping Wan, Yesen Li, Yuhong Xu, Yuanjiang Pan. Design and Synthesis of Cyclo[-Arg-Gly-Asp-Ψ(triazole)-Gly-Xaa-] Peptide Analogues by Click Chemistry. Tetrahedron 2008, 64, 10728-10734.

　　[17] Cungui Cheng, Gonglei Sun, Jieping Wan, Cuirong Sun. Facile CuI-Catalyzed Arylation of Azoles and Amides Using Simple Enaminones as Efficient Ligands. Synlett 2009, 2663-2668.

　　[18] Yuanpo Tai, Saifeng Pei, Jieping Wan, Xiaoji Cao, Yuanjiang Pan. Fragmentation study of protonated chalcones by atmospheric pressure chemical ionization and tandem mass spectrometry. Rapid Communications in Mass Spectrometry 2006, 20, 994-1000.

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