常州大学制药与生命科学学院导师介绍：徐华栋

　　CONTACT:

　　School of Pharmaceutical and Life Sciences

　　Changzhou University （常州大学制药与生命科学学院）

　　Changzhou, Jiangsu 213164, China

　　Cell: ***********

　　Email Address：huadongxu@gmail.com

　　 xuhd@cczu.edu.cn

　　RESEARCH INTERESTS:

　　Organic methodology research by Organometallic Chemistry and Sugar Chemistry.

　　(有机方法学研究，重点运用金属有机化学方法和糖化学方法)

　　Drug research and development for treating cancers.

　　(新型抗癌药物的研究)

　　FUNDINGS:

　　2013国家自然科学基金面上项目（项目批准号：21272077）

　　2011国家自然科学青年基金（项目批准号：21002032）

　　2011浦江人才基金 （11PJ1403100）

　　PROFESSIONAL EXPERIENCE:

　　2012-presentProfessor

　　School of Pharmaceutical and Life Sciences, Changzhou University, China.

　　2010-2012Associate Professor

　　East China Normal University, Shanghai. (华东师范大学)

　　2009-2010Senior Research Scientist

　　PharmaResources Shanghai CO. LTD.(上海鸿博智源医药研究有限公司)

　　2007-2009Postdoctoral Research Associate

　　Chemistry Department, University of Wisconsin-Madison, USA. (威斯康星大学-麦迪逊分校)

　　2003-2007Teaching Assistant and Research Assistant

　　Chemistry Department, University of Illinois at Chicago, USA．(伊利诺依大学-芝加哥分校)

　　2000-2003Assistant Researcher

　　Daiwei Ma’ s Research Group, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (中国科学院上海有机化学研究所)

　　EDUCATIONAL BACKGROUND:

　　2007Ph.D in Organic Chemitry, Chemistry Department, University of Illinois at Chicago, USA. (伊利诺依大学-芝加哥分校)

　　2000 Master in Organic Chemistry, East China University of Science and Technology (Shanghai, P. R. China) （华东理工大学）

　　1998 Bachelor in Chemistry, Lanzhou University ( 兰州大学)

　　SELECTED PUBLICATIONS:

　　1．Synthesis of β-diazo-α-ketoamide and their cyclopropanation reaction with alkenes. Chen, X.; Hu, W.; Li, X.*; Xu, H-D.*Chin. J. Syn. Chem. 2012, 20, 1.

　　2．3-Diazo-N-[(2S)-1-hydroxypropan-2-yl]-2-oxopropanamide. Chen, X.; Hu, W.; Li, X.*; Xu, H-D.* Acta Cryst. 2011, E67, o1192.

　　3．Diastereoselectively Switchable Enantioselective Trapping of Carbamate Ammonium Ylides with Imines, Jiang, J.; Xu, H-D.; Xi, J.; Hu, W.* J. Am. Chem. Soc. 2011, 133, 8428.

　　4．Thermodynamic Control of the Electrocyclic Ring Opening of Cyclobutenes: C=X Substituents at C-3 Mask the Kinetic Torquoselectivity Um, J. M.; Xu, H-D.; Houk, K. N. *; Tang, W. * J. Am. Chem. Soc. 2009, 131, 6664.

　　5．DABCO-Catalyzed 1,4-Bromolactonization of Conjugated Enynes: Highly Stereoselective Formation of a Stereogenic Center and an Axially Chiral Allene, Zhang, W.; Xu, H-D.; Tang, W. * J. Am. Chem. Soc. 2009, 131, 3832.

　　6．Highly Selective Synthesis of Cyclobutenes via Transition Metal Catalyzed Rearrangement of Cyclopropyl Metal Carbenes. Xu, H-D., Zhang, W., Shu, D., Werness, J. B. and Tang, W. * Angew. Chem. 2008,47,8933.

　　7．Direct stereocontrolled synthesis of 3-amino-3-deoxy-β-mannopyranosides: importance of the nitrogen protecting group on stereoselectivity. Crich, D. *; Xu, H-D. J. Org. Chem. 2007, 72, 5183

　　8．Total synthesis and structural verification of some novel branched alkanes with quaternary carbons isolated from diverse geological sources. Crich, D. *; Xu, H-D.; Kenig, F. J. Org. Chem. 2006, 71, 5016.

　　9．Chiral 1,2,3,4-tetrahydroquinolinyl-oxazoline ligands for Ru-catalyzed asymmetric transfer hydrogenation of ketones. Zhou, Y.; Tang, F.; Xu, H-D.; Wu, X.; Ma, J.; Zhou Q. * Tetrahedron: Asymmetry 2002, 13, 469.

　　10．Remote substituent effect in palladium/pyridinyl-oxazolines catalyzed asymmetric allylic alkylation. Li, Z.; Tang, F.; Xu, H-D.; Wu, X.; Zhou, Q. *; Chan, A. S. C. J. Mol. Catal. A. 2002, 1-7, 3756.

　　11．A short synthesis of the HIV-protease inhibitor nelfinavir via a distereoselective addition of ammonia to the α-β-unsaturated sulfoxide derived from (R)-glyceraldehyde acetonide. Ma, D. *; Zou, B.; Zhu, W.; Xu, H-D. Tetrahedron Lett. 2002, 43, 8511.

　　12．Asymmetric hydroarylation of norbornene derivatives catalyzed by palladium complexes of chiral quinolinyl-oxazolines. Wu, X.; Xu, H-D.; Tang, F.; Zhou, Q．* Tetrahedron Asymmetry 2001, 12, 2565.

　　13．Enantioselecive Heck-type hydroarylation of norbornene with phenyl iodide catalyzed by palladium/quinolinyloxazolines. Wu, X.; Xu, H-D.; Zhou, Q. *; Chan, A. S. C. Tetrahedron: Asymmetry 2000, 11, 1255.

　　*如果发现导师信息存在错误或者偏差，欢迎随时与我们联系，以便进行更新完善。联系方式>>