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中科院动物研究所导师介绍:彭景楩


  姓名:彭景楩
  学科:发育生物学
  电话/传真:+86-10-64807183 /
  电子邮件:pengjp@ioz.ac.cn
  通讯地址:北京市朝阳区北辰西路1号院5号
  中国科学院动物研究所 计划生育生殖生物学国家重点实验室 100101
  更多信息:生殖免疫研究组 个人页面 English

  简历:
  彭景楩,男,1958年生,汉族,湖北武汉人,博士,中国科学院动物研究所研究员、博士生导师、计划生育生殖生物学国家重点实验室生殖免疫研究组组长。
  主要从事生殖分子免疫学领域的研究,研究兴趣:妊娠过程中母胎识别与免疫豁免的分子表达及调控机制,探索母-胎免疫耐受机制。基因疫苗机理与应用的研究:以基因疫苗为技术平台,研究免疫控制生育、免疫抗生殖系统肿瘤的分子机理。1996年赴美从事神经与生殖内分泌免疫关系的研究,在Georgetown大学医学中心和Rutgers大学分子生物学中心完成二项博士后研究。近几年来承担和完成的研究课题有:近几年来承担和完成的研究课题有:科技部863计划课题2项、国家自然科学基金面上项目4项(已完成3项)、973项目子课题1项和国家重大科学研究计划项目课题(项目首席科学家)。04年入选“新世纪百千万人才工程国家级人选”,同年荣获“中央国家机关五一劳动奖章”荣誉称号,享受国务院政府特殊津贴;03年、06年两次获国家人口和计划生育科技工作先进个人荣誉称号;2011年获得国家人口和计划生育委员会全国人口和计划生育优秀科技成果奖壹等奖。十多年来,发表论文62篇。其中SCI论文41篇;申报受理国家发明专利2项,获国家发明专利5项;参编学术著作国内外各一部。

  承担科研项目情况:
  •973项目(2006CB504006):滋养层侵入的分子基础与肿瘤侵润
  •重大科学研究计划项目(2006CB944007):母胎免疫豁免和排斥的分子机理
  •国家自然基金面上项目(30770246):CYP26A1在大鼠胚胎植入中的作用及其分子机理的研究

  代表论著:
  1.Gao-Feng Xiong,Yan-Shuai Zhang,Bing-Chen Han,Wen Chen,Ying Yang,Jing-Pian Peng*(2011).Estradiol-regulated gene praline-rich acid protein 1 repressed by class I histone deacetylase and its action in peri-implantation mouse uterus.Mol Cell Endocrinol.331:23-33
  2.Hong Fei-Xia,Jing-Jing Ma,Jing Sun,Ying Yang,Jing-Pian Peng*(2010).Retinoic acid metabolizing enzyme CYP26A1 is implicated in rat embryo implantation Hum Reprod,25(12):2985-2998
  3.Wen Chen,Bing-Chen Han,Rong-Chun Wang,Gao-Feng Xiong,Jing-Pian Peng*,(2010)The role of secretory protease inhibitor SPINK3 in mouse uterus during early pregnancy.Cell Tissue Res 341:441-451.
  4.Bing-Chen Han,Hong Fei-Xia,Jing Sun,YingYang,Jing-Pian Peng*,(2010)Retinoic Acid-Metabolizing Enzyme Cytochrome P450 26a1 (Cyp26a1)Is Essential for Implantation:Functional Study of Its Role in Early Pregnancy.J.Cell.Physiol.223:471–479.
  5.Hong Fei-Xia,Jing Sun,Quan-Hong Sun,Ying Yang,Jing-Pian Peng*(2008)Implantation associated gene-1 (Iag-1):a novel gene involved in the early process of embryonic implantation in rat.Hum Reprod,23(7):1581–1593.
  6.Li Xu;Shu-Qun Shi;Ying Yang;Jing-Pian Peng* (2007)Researches on four cDNA fragments from rabbit ZP3:their immunogenicity and effects on fertility,Fertil and Steril.87(2):381-390.
  7.Shu-Qun Shi,Li Xu,Gang Zhao,Yang Ying,Jing-Pian Peng*,(2006)Apoptosis and tumor inhibition induced by human chorionic gonadotropin beta in mouse breast carcinoma.J Mol Medi.-jmm.84:933–941
  8.Jian-Jun Chang,6.Jing-Pian Peng* YingYang,Jing-LingWang,LiXu (2006)Study on the Anti-fertility Effects of the Plasmid DNA Vaccine Expressing Partial brLDH-C4.Reprod.131:183–192.
  9.Quan-Hong Sun,Jing-Pian Peng*,Hong-Fei Xia,(2005)Effect on expression of RT1-A and RT1-DM molecules treatment with interferon gamma at the maternal-fetal interface of pregnant rat.Hum Reprod,20(9):2639-2647.
  10.Ruo-lan Xiang,Fei Zhou,Ying Yang and Jing-pian Peng*,2.(2003)Construction of the Plasmid pCMV4-rZPC` DNA Vaccine and Analysis of its Contraceptive Potential,3.Biol Reprod,68(5):1578-1524.
  11.Jing Sun,Hong-Fei Xia,YingYang,Jing-Pian Peng,*(2008)The antifertility effects of DNA vaccine-induced immune responses against uroguanylin.Vaccine.online on june,2008)
  12.Hong-Fei Xia,? Jing Sun,Quan-Hong Sun,Ying Yang,Jing-Pian Peng*(2008)Implantation associated gene-1 (Iag-1):a novel gene involved in the early process of embryonic implantation in rat.Human Reproduction.23(7):1581-1593.
  13.Quan-Hong Sun ?Jing-Pian Peng* Hong-Fei Xia Ying Yang,(2007)Interferon gamma promote apoptosis of uterus and placenta in pregnant rat and human cytotrophoblast cells.Journal of Interferon & Cytokine Research.27:567-578.
  14.Hong-Fei Xia,Quan-Hong Sun and Jing-Pian Peng,* (2007)Effect of interferon-g treatment on the expression of interleukin-1b at the maternal–fetal interface of pregnant rats.Reproduction,Fertility and Development.19,510–519.
  15.Li Xu,Shu-Qun Shi,Ying Yang,Jing-Pian Peng*,(2007)Researches on four cDNA fragments from rabbit ZP3:their immunogenicity and effects on fertility,Fertility and Sterility.87(2):381-390.
  16.Shu-Qun Shi,Li Xu,Gang Zhao,Yang Ying,Jing-Pian Peng*,(2006)Apoptosis and tumor inhibition induced by human chorionic gonadotropin beta in mouse breast carcinoma.Journal of Molecular Medicine.-jmm.84:933–941.
  17.Gang Zhao,Shu-Qun Shi,Ying Yang,and Jing-Pian Peng,* (2006)M and N proteins of SARS coronavirus induce apoptosis in HPF cells.Cell Biol Toxicol 22:313–322.
  18.Hong-Fei Xia,Jing-Pian Peng *,Quan-Hong Sun ,Ying Yang ,and Mei-Ling Liu,(2006)Effects of IL-1 beta on RT1-A/RT1-DM at the maternal-fetal interface during pregnancy in rats.Frontiers in Bioscience.11,2868-2875.
  19.Shu-Qun Shi,Jing-PianPeng,*Yin-Chuan Li,Chuan Qin,Guo-Dong Liang,Li Xu,YingYang,Jin-LingWang,Quan-Hong Sun,(2006)The expression of membrane protein augments the specific responses induced by SARS-CoV nucleocapsid DNA immunization.Mol Immunol.43(11):1791-1798.

  写给考生的话:
  本人主要从事生殖分子免疫学领域的研究,研究兴趣主要集中在:1)妊娠过程中母胎识别与免疫豁免的分子表达及调控机制;2)基因疫苗机理与应用的研究:研究免疫控制生育、免疫抗生殖系统肿瘤的分子机理。
  如果您对我所从事的研究方向感兴趣,真诚欢迎您报考。几多耕耘,几分收获,期盼我们在未来的3-5年中一起努力工作,不断求索,将我们组的研究工作推向一个新高度,我们期盼你的加入!

  *如果发现导师信息存在错误或者偏差,欢迎随时与我们联系,以便进行更新完善。联系方式>>

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