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2018年广西大学动物科学技术学院生物专业考研调剂信息:周磊教授课题组

  招生人数:5

  招生简介:

  课题组长简介

  周磊,男,37岁,广西大学动物科学技术学院教授,博士生导师。入选广西“百人计划”,获广西青年五四奖章,中国畜牧兽医学会动物生理生化学分会理事、遗传育种学分会理事。先后留学德国糖尿病研究中心(杜塞尔多夫)、法国原子能委员会(巴黎)、美国宾夕法尼亚大学(费城)。2013年作为学术带头人引进到广西大学,建立分子营养课题组。联系方式:***********,************;zhoulei@gxu.edu.cn。

  研究方向

  营养组学研究(功能基因组、表观基因组、蛋白质组、蛋白质修饰组)

  动物重要经济性状的遗传改良

  动物生理代谢调控

  社会兼职

  中国畜牧兽医学会动物遗传育种学分会理事

  中国畜牧兽医学会动物生理生化学分会理事

  硕士生要求

  1. 生物或医学等相关专业

  2. 对生命科学研究有浓厚的兴趣

  3. 做事认真踏实,责任心强,有良好的与人相处和沟通的能力及团队合作精神

  4. 具备良好的英语读写能力

  相关待遇

  硕士生除享有国家和课题组固定津贴,根据科研绩效还享有课题组额外奖励

  课题组情况

  分子营养课题组依托广西大学动物科学技术学院和亚热带农业生物资源保护与利用国家重点实验室,研究方向为糖脂代谢调控,在医学上主要针对肥胖、糖尿病、脂肪肝等代谢疾病;在畜牧上研究脂肪性状对繁殖、肉质、瘦肉率的调控。已在Hepatology、Nucleic Acids Research等高水平杂志上发表多篇论文。课题组长周老师入选广西自治区百人计划、广西大学杰出人才培养计划,团队承担多项国家级、省部级研究课题。

  1. 周老师从科研思路、实验技能和论文写作方面亲自指导学生,与学生一起做研究,全方位培养学生

  2. 课题组与美国、德国等多个课题组保持着长期合作关系,优秀研究生和博士后根据项目进展和合作需要,有机会赴德国或美国进行联合培养或合作研究,毕业或出站后尽力推荐去国外一流课题组继续深造

  3. 博士后和研究生每年至少参加一次国内学术会议

  4. 课题组工作氛围轻松友善,为团队成员提供实现自身价值的机会及发展空间

  5. 先进的课题组运行模式,每个成员都有独立项目

  6. 较为充足的研究经费(详见主持项目)

  7. 充足的实验空间和优良的实验设备,具有课题组专用的洁净室和动物房。

  主持项目

  1. 广西大学高层次专业技术人才培养工程“杰出人才培养计划”,2015/08-2020/07。

  2. 国家自然科学基金,2017/01-2020/12。

  3. 广西高校引进海外高层次人才“百人计划”,2014年。

  4. 广西自然科学基金重点项目,2014/06-2017/05。

  5. 广西大学科研基金(引进人才项目),2013/07-2018/06。

  6. 欧洲糖尿病研究基金项目(EFSD,欧洲基金会资助),2012/01-2013/06。

  7. 教育部博士点新教师基金,2011/01-2013/12。

  8. TANITA健康体重基金(日本基金会资助),2009/10-2010/10。

  9. 欧洲糖尿病研究基金项目(EFSD,欧洲基金会资助),2006/10-2007/03。

  近5年代表作

  1. Lei Zhou*, Xiaolan Yu, Qingjie Meng, Hongqiang Li, Congcong Niu, Yun Jiang, Yuxi Cai, Minghui Li, Qiang Li, Chaoqiang An, Le Shu, Ao Chen, Handong Su, Yin Tang, Shen Yin, Silja Raschke, Kristin Eckardt, Juergen Eckel, Zaiqing Yang*. Resistin reduces mitochondria and induces hepatic steatosis in mice by the protein kinase C/protein kinase G/p65/PPAR gamma coactivator 1 alpha pathway. Hepatology. 2013, 57: 1384-1393. SCI收录,IF:13.246

  2. Lei Zhou, Gwenaelle Le Roux, Cecile Ducrot, Stephane Chedin, Jean Labarre, Michel Riva, Christophe Carles*. Repression of class I transcription by cadmium is mediated by the Protein Phosphatase 2A. Nucleic Acids Res. 2013, 41: 6087–6097. SCI收录,IF:10.162

  3. Lin Yu, Lina Tai, Lifang Zhang, Yi Chu, Yixing Li*, Lei Zhou*. Comparative analyses of long non-coding RNA in lean and obese pig. Oncotarget. 2017, 8(25): 41440-41450. SCI收录,IF:5.168

  4. Yuxiang Zhang, Yixing Li, Lin Yu, Lei Zhou*. Association between serum resistin concentration and hypertension: A systematic review and meta-analysis. Oncotarget. 2017, 8(25): 41529-41537. SCI收录,IF:5.168

  5. Li Y, Luo Z, Wu X, Zhu J, Yu K, Jin Y, Zhang Z, Zhao S, Zhou L*. Proteomic Analyses of Cysteine Redox in High-Fat-Fed and Fasted Mouse Livers: Implications for Liver Metabolic Homeostasis. J Proteome Res. 2018, 17(1): 129-140. SCI收录,IF:4.268

  6. Yixing Li, Yi Chu, Lin Yu, Huifang Kang, Lei Zhou*. Transcriptomic analysis of Bama pig's liver in various nutritional status reveals a metabolic difference of fatty acid. Food & Function. 2017, 8: 3480-3490. Cover Paper, SCI收录,IF:3.247

  7. Qiang Li, Yuxi Cai, Jing Huang, Xiaolan Yu, Jun Sun, Zaiqing Yang*, Zhou L*. Resistin impairs glucose permeability in EA.hy926 cells by downregulating GLUT1 expression. Mol Cell Endocrinol. 2016, 434: 127-34. SCI收录,IF:3.754

  8. Jiang Y, Lu L, Hu Y, Li Q, An C, Yu X, Shu L, Chen A, Niu C, Zhou L*, Yang Z*. Resistin Induces Hypertension and Insulin Resistance in Mice via a TLR4-Dependent Pathway. Sci Rep. 2016, 6: 22193. SCI收录,IF:4.259

  9. Yixing Li, Huifang Kang, Yi Chu, Yi Jin, Lifang Zhang, Ranran Yang, Zhiwang Zhang, Shuhong Zhao, Lei Zhou*. Cidec differentially regulates lipid deposition and secretion through two tissue-specific isoforms. Gene. 2018, 641C: 265-271. SCI收录,IF:2.415

  10. Li H, Chen A, Shu L, Yu X, Gan L, Zhou L*, Yang Z*. Translocation of CIDEC in hepatocytes depends on fatty acids. Genes Cells. 2014, 19(11): 793-802. SCI收录,IF:1.993

  11. Y Li, L Zhou*, Vitamin D Deficiency, Obesity and Diabetes. Cell Mol Biol. 2015, 61(3): 35-38. SCI收录,IF:0.92

  其他发表论文

  1. Lei Zhou, Henrike Sell, Kristin Eckardt, Zaiqing Yang, Jürgen Eckel. Conditioned medium obtained from in vitro differentiated adipocytes and resistin induce insulin resistance in human hepatocytes. FEBS letters. 2007, 581: 4303-4308. SCI收录,IF:3.623

  2. Lei Zhou, Qingjie Meng, Tao Qian, Zaiqing Yang. Ginkgo biloba extract enhances glucose tolerance in hyperinsulinism-induced hepatic cells. J Nat Med. 2011, 65(1): 50-6. SCI收录,IF:1.982

  3. Lei Zhou, Yixing Li, Tao Xia, Shengqiu Feng, Xiaodong Chen, Zaiqing Yang. Resistin Overexpression Impaired Glucose Tolerance in Hepatocytes. Eur Cytokine Netw. 2006, 17(3): 189-95. SCI收录,IF:2.364

  4. Lei Zhou, Yixing Li, Tao Nie, Shengqiu Feng, Huaping Chen, Zaiqing Yang. Clenbuterol inhibits SREBP-1c expression by activating CREB1. J BIOCHEM MOL BIOL. 2007, 40(4): 525-31. SCI收录,IF:2.021

  5. Lei Zhou, Lijie Zhang, Qingjie Meng, Congcong Niu, Dan Jin, An Yu, Li gan, Zaiqing Yang. C/EBP? promotes transcription of the porcine perilipin5 gene. Mol Cell Endocrinol. 2012, 364:28-35. SCI收录,IF:3.754

  6. Lei Zhou, Tao Xia, Yixing Li, Xiaodong Chen, Yin Peng, Zaiqing Yang. Transcriptional Regulation of the Resistin Gene. Domest Anim Endocrinol. 2006, 30(2): 98-107. SCI收录,IF:1.644

  7. Yanling Wu, Qinqiang Long, Bin Feng, Xiaoyue Zhu, Zifeng Zheng, Sumin Gao, Mingju Gao, Li Gan, Lei Zhou, Zaiqing Yang. Molecular cloning and characterization of the anti-obesity gene adipose in pig. Gene. 2012, 509: 110-9. SCI收录,IF:2.415

  8. Chen Z, Gao X, Lei T, Chen X, Zhou L, Yu A, Lei P, Zhang R, Long H, Yang Z. Molecular characterization, expression and chromosome localization of porcine PNPLA3 and PNPLA4. Biotechnol Lett. 2011, 33(7): 1327-37. SCI收录,IF:1.73

  9. Zhang J, Lei T, Chen X, Peng Y, Long H, Zhou L, Huang J, Chen Z, Long Q, Yang Z. Resistin Up-Regulates COX-2 Expression via TAK1-IKK-NF-kappaB Signaling Pathway. Inflammation. 2010, 33(1): 25-33. SCI收录,IF:2.955

  10. Qi YM, Lei T, Zhou L, Chen XD, Long QQ, Long H, Jin D, Gan L, Yang ZQ. Genomic organization, alternative splicing and tissues expression of porcine CREB3L4 gene. Mol Biol Rep. 2009, 36(7): 1881-8. SCI收录,IF:1.828

  11. Y. H. Li, T. Lei, X. D. Chen, T. Xia, Q. Q. Long, J. Zhang, S. Q. Feng, Y. Peng, L. Zhou, Z. Q. Yang. Molecular cloning, chromosomeal location and expression pattern of porcine CIDEa and CIDEc. Mol Biol Rep. 2009, 36(3): 575-82. SCI收录,IF:1.828

  12. Qi M, Lei T, Zhou L, Chen XD, Long H, Long QQ, Zhang RR, Yang ZQ, Gan L. Cloning, Characterization, Chromosomal Mapping and Tissue Transcription Analysis of Porcine CREB2 and CREB3 Genes. Folia Biol. 2009, 55(4): 137-44. SCI收录,IF:0.939

  13. Huaping Chen, Wenshu Yao, Dan Jin, Tao Xia, Xiaodong Chen, Ting Lei, Lei Zhou, Zaiqing Yang. Cloning, Expression Pattern, Chromosomal Localization, and Evolution Analysis of Porcine Gnaq, Gna11, and Gna14. Biochem Genet. 2008, 46(7-8): 398-405. SCI收录,IF:1.543

  14. Y Li, L Zhou, Y Li, D Chen, X Tan, L Lei and J Zhou. A Nodule-Specific Plant Cysteine Proteinase, AsNODF32, Is Involved in Nodule Senescence and Nitrogen Fixation Activity of the Green Manure Legume Astragalus sinicus. New Phytologist. 2008, 180: 185-192. SCI收录,IF:7.33

  15. Huaping Chen, Tao Xia, Lei Zhou, Xiaodong Chen, Li Gan, Wenshu Yao, Yin Peng, and Zaiqing Yang. Gene organization, alternate splicing and expression pattern of porcine visfatin gene. Domest Anim Endocrinol. 2007; 32: 235-45. SCI收录,IF:1.644

  16. HW Yang, T Xia, ZL Chen, SQ Feng, Y Peng, L Zhou, L Gan, and ZQ Yang. Cloning, chromosomal localization and expression patterns of porcine Kruppel-like factors 4, -5, -7 and the early growth response factor 2. Biotechnol Lett. 2007; 29(1): 157-63. SCI收录,IF:1.73

  17. Feng SQ, Chen XD, Xia T, Gan L, Qiu H, Dai MH, Zhou L, Peng Y, Yang ZQ. Cloning, chromosome mapping and expression characteristics of porcine ANGPTL3 and -4. Cytogenet Genome Res. 2006; 114(1): 44-9. SCI收录,IF:1.354

  申请者可通过电子邮件提交个人简历,有意者可通过以下方式联系周老师,***********,************(办公室);zhoulei@gxu.edu.cn。

  热忱欢迎有意在代谢及组学等领域进行探索的各位优秀人才!

  期待您的加入!

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