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中国科学院成都生物研究所博士生导师简介:孙健研究员

简介:
    孙 健,男,1971年出生,四川省仪陇县人。1992年毕业于四川大学化学系,1995年在中科院成都有机化学研究所获得硕士学位,1998年在中科院化学研究所获得博士学位,并于同年赴美国Scripps研究所从事博士后研究工作,2001年6月聘任美国Sunesis制药公司Research Scientist。2003年入选中国科学院“百人计划”(“引进国外杰出人才”) ,并于2004年回国。现任中科院成都生物研究所研究员、博士生导师、天然产物研究中心主任。主要从事不对称合成、天然产物合成及方法学研究、新药开发研究。已在国际重要刊物上发表SCI论文三十余篇,论文已被SCI他引近300余次,已申请国际发明专利四项、国内发明专利四项。

近期代表论文:
(1) P. Wu, Z. Wang, M. Cheng, L. Zhou, J. Sun*, “Development of Highly Enantioselective New Lewis Basic N-Formamide Organocatalysts for Hydrosilylation of Imines with an Unprecedented Substrate Profile”, Tetrahedron 2008, 64, 11304-11312.
(2) C. Wang, X. Wu, L. Zhou, J. Sun*, “A Highly Enantioselective Organocatalytic Method for Reduction of Aromatic N-Alkyl Ketimines”, Chem. Eur. J. 2008, 14, 8789-8792.
(3) D. Pei, Y. Zhang. S. Wei, M. Wang, J. Sun*, “Rationally-Designed S-Chiral Bissulfinamides as Highly Enantioselective Organocatalysts for Reduction of Ketimines”, Adv. Synth. Catal. 2008, 350, 619-623.
(4) L. Zhou, Z. Wang, S. Wei, J. Sun*, “Evolution of Chiral Lewis Basic N-Formamide as Highly Effective Organocatalyst for Asymmetric Reduction of Both Ketones and Ketimines with an Unprecedented Substrate Scope”, Chem. Commun.2007, (28), 2977 - 2979.
(5) Z. Wang, S. Wei, C. Wang, J. Sun*, “Enantioselective Hydrosilylation of Ketimines Catalyzed by Lewis Basic C2-Symmetric Chiral Tetraamide”, Tetrahedron: Asymmetry 2007, 18, 705-709.
(6) D. Pei, Z. Wang, S. Wei, Y. Zhang, J. Sun*, “S-Chiral Sulfinamides as Highly Enantioselective Organocatalysts”, Org. Lett. 2006, 8(25), 5913-5915.
(7) Z. Wang, M. Cheng, P. Wu, S. Wei, J. Sun*, “L-Piperazine-2-Carboxylic Acid Derived N-Formamide as Highly Enantioselective Lewis Basic Catalyst for Hydrosilylation of N-Aryl Imines with an Unprecedented Substrate Profile”, Org. Lett. 2006, 8(14), 3045-3048.
(8) Z. Wang, X. Ye, S. Wei, P. Wu, A. Zhang, J. Sun*, “A Highly Enantioselective Lewis Basic Organocatalyst for Reduction of N-Aryl Imines with Unprecedented Substrate Spectrum”, Org. Lett. 2006, 8(5), 999-1001.
(9) C. Cheng, J. Sun*, C. Wang, Y. Zhang, S. Wei, F. Jiang, Y. Wu, “Protonated N’-benzyl-N’-prolyl Proline Hydrazide as Highly Enantioselective Catalyst for Direct Asymmetric Aldol Reaction”, Chem. Commun.2006, (2), 215 - 217.

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电子信箱:sunjian@cib.ac.cn
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